C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytokine-dependent hematopoietic cell linker
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109684 CLNK 9606 - 4:10486395-10684865 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000226951 CLNK-001 10486395-10684865 protein_coding
  ENST00000442825 CLNK-201 10490215-10598681 protein_coding
  ENST00000507719 CLNK-002 10531413-10656561 protein_coding
  ENST00000515667 CLNK-003 10486874-10517465 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000226951ENST00000442825ENST00000507719ENST00000515667
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000226951 N/A 0.279±0.00 N/A 0.007±0.00 0.041±0.00 N/A 1.176±0.00 0.006±0.00 0.039±0.01 N/A 0.049±0.04 0.010±0.00 N/A
ENST00000442825 N/A N/A N/A N/A N/A N/A 0.253±0.00 N/A 0.126±0.00 N/A N/A 0.186±0.04 N/A
ENST00000507719 0.080±0.00 N/A 0.076±0.00 0.264±0.19 0.094±0.00 0.039±0.00 N/A 0.115±0.06 0.484±0.00 0.037±0.00 0.075±0.00 0.364±0.00 0.338±0.00
ENST00000515667 0.037±0.00 N/A 0.012±0.00 0.014±0.00 0.006±0.00 0.002±0.00 0.015±0.00 0.008±0.00 N/A N/A 0.028±0.03 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008UW CIL_0008UW_0001 VISTA 4:10015545-10620462
CIL_0001XH CIL_0001XH_0001 CGP 4:10439874-10684865
CIL_0001XI CIL_0001XI_0001 CGP 4:10486395-11429765

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005070 NAS SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005622 NAS intracellular
GO:0006955 NAS immune response
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0009967 NAS positive regulation of signal transduction
GO:0035556 IDA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091321 CLNK cytokine-dependent hematopoietic cell linker protein_coding Danio_rerio
ENSMUSG00000039315 Clnk cytokine-dependent hematopoietic cell linker protein_coding Mus_musculus

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