C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pannexin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110218 PANX1 9606 + 11:94128928-94181972 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227638 PANX1-001 94128928-94181972 protein_coding
  ENST00000436171 PANX1-002 94128929-94181966 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227638ENST00000436171
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227638 2.423±0.00 N/A 1.361±0.00 3.608±1.67 2.057±1.05 2.648±0.77 1.330±0.76 2.272±1.39 2.570±0.52 8.921±0.00 1.208±0.00 4.211±1.23 5.240±0.47 5.526±0.25
ENST00000436171 N/A 1.905±0.00 N/A N/A 0.610±0.00 N/A N/A 1.041±0.00 0.893±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002C1 CIL_0002C1_0002 CGP 11:94021361-94181972

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0002931 IEA response to ischemia
GO:0003779 IEA actin binding
GO:0005102 IPI receptor binding
GO:0005243 IEA gap junction channel activity
GO:0005262 IMP calcium channel activity
GO:0005515 IEA protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0005921 IEA gap junction
GO:0006812 IDA cation transport
GO:0006816 IMP calcium ion transport
GO:0007267 IEA cell-cell signaling
GO:0007268 TAS synaptic transmission
GO:0015267 IEA channel activity
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0022840 IMP leak channel activity
GO:0032059 IDA bleb
GO:0033198 IEA response to ATP
GO:0034214 IDA protein hexamerization
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0043234 IEA protein complex
GO:0044325 IEA ion channel binding
GO:0045087 TAS innate immune response
GO:0046982 IEA protein heterodimerization activity
GO:0050715 IEA positive regulation of cytokine secretion
GO:0050717 IEA positive regulation of interleukin-1 alpha secretion
GO:0050718 IDA positive regulation of interleukin-1 beta secretion
GO:0051015 IEA actin filament binding
GO:0055077 IDA gap junction hemi-channel activity
GO:0055085 IEA transmembrane transport
GO:0070588 IEA calcium ion transmembrane transport
GO:0097110 IEA scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014910 panx1b pannexin 1b protein_coding Danio_rerio
ENSDARG00000025285 panx1a pannexin 1a protein_coding Danio_rerio
ENSMUSG00000031934 Panx1 pannexin 1 protein_coding Mus_musculus

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