C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 4 gamma, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110321 EIF4G2 9606 - 11:10797050-10809110 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000339995 EIF4G2-001 10797054-10809110 protein_coding
  ENST00000396525 EIF4G2-002 10797170-10808708 protein_coding
  ENST00000524932 EIF4G2-003 10803561-10808940 protein_coding
  ENST00000525606 EIF4G2-031 10797728-10799626 retained_intron
  ENST00000525681 EIF4G2-008 10797053-10807462 protein_coding
  ENST00000525972 EIF4G2-013 10804364-10808923 processed_transcript
  ENST00000525995 EIF4G2-018 10804985-10808630 processed_transcript
  ENST00000526148 EIF4G2-006 10797050-10807973 protein_coding
  ENST00000527015 EIF4G2-023 10803942-10804606 retained_intron
  ENST00000527419 EIF4G2-015 10804297-10808923 protein_coding
  ENST00000527526 EIF4G2-020 10804927-10807876 protein_coding
  ENST00000528562 EIF4G2-011 10804372-10808924 nonsense_mediated_decay
  ENST00000528839 EIF4G2-029 10798992-10800482 protein_coding
  ENST00000530211 EIF4G2-012 10804916-10808923 protein_coding
  ENST00000530564 EIF4G2-027 10800531-10801588 retained_intron
  ENST00000530702 EIF4G2-010 10804946-10808929 protein_coding
  ENST00000531180 EIF4G2-028 10800092-10801015 protein_coding
  ENST00000531416 EIF4G2-005 10801055-10808084 protein_coding
  ENST00000531507 EIF4G2-014 10804340-10808923 processed_transcript
  ENST00000531647 EIF4G2-021 10802060-10807334 nonsense_mediated_decay
  ENST00000532082 EIF4G2-004 10803261-10808309 protein_coding
  ENST00000532120 EIF4G2-026 10797712-10802346 processed_transcript
  ENST00000532152 EIF4G2-022 10804292-10806263 retained_intron
  ENST00000532349 EIF4G2-024 10803512-10804538 retained_intron
  ENST00000532383 EIF4G2-007 10797054-10808028 retained_intron
  ENST00000532570 EIF4G2-009 10804381-10808940 protein_coding
  ENST00000533485 EIF4G2-019 10806503-10807677 retained_intron
  ENST00000534246 EIF4G2-016 10807074-10808919 retained_intron
  ENST00000534272 EIF4G2-030 10798992-10800295 processed_transcript
  ENST00000534470 EIF4G2-032 10798743-10799361 retained_intron
  ENST00000534605 EIF4G2-025 10804181-10805949 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000339995ENST00000396525ENST00000525681ENST00000531416ENST00000531647
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000339995 40.957±0.00 26.885±0.00 N/A 46.259±25.31 50.037±24.24 64.847±46.79 70.773±36.89 43.084±24.16 36.224±6.33 55.679±39.51 50.067±15.68 65.679±23.52 82.750±10.20 59.757±42.38
ENST00000396525 27.972±0.00 22.252±0.00 N/A 17.313±0.00 30.516±0.00 27.161±0.00 63.598±0.00 29.066±19.22 20.588±0.00 41.293±0.00 30.212±0.00 34.416±17.99 54.282±35.72 41.607±0.00
ENST00000525681 33.416±0.00 59.553±0.00 19.472±0.00 26.525±0.00 36.834±7.78 42.137±1.25 13.446±0.00 23.883±14.70 13.583±0.00 45.899±0.00 26.979±10.27 47.405±2.09 55.434±4.94 53.800±21.30
ENST00000531416 N/A N/A 25.541±0.00 N/A N/A N/A N/A N/A N/A N/A 24.317±0.00 N/A N/A N/A
ENST00000531647 N/A N/A 121.334±0.00 56.693±0.00 N/A N/A N/A N/A 123.450±0.00 100.163±0.00 N/A 113.422±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000417 CIL_000417_0002 CGP 11:10750987-10809110

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0003743 IEA:IDA translation initiation factor activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006413 IEA translational initiation
GO:0006446 IDA regulation of translational initiation
GO:0007050 TAS cell cycle arrest
GO:0008135 IDA translation factor activity, nucleic acid binding
GO:0008219 TAS cell death
GO:0016020 IDA membrane
GO:0016281 IDA eukaryotic translation initiation factor 4F complex
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020377 eif4g2a eukaryotic translation initiation factor 4, gamma 2a protein_coding Danio_rerio
ENSDARG00000057167 eif4g2b eukaryotic translation initiation factor 4, gamma 2b protein_coding Danio_rerio
ENSMUSG00000005610 Eif4g2 eukaryotic translation initiation factor 4, gamma 2 protein_coding Mus_musculus

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