C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cysteinyl-tRNA synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110619 CARS 9606 - 11:3000922-3057613 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000278224 CARS-002 3000929-3057418 protein_coding
  ENST00000380525 CARS-004 3000922-3057437 protein_coding
  ENST00000397111 CARS-001 3000922-3057613 protein_coding
  ENST00000439280 CARS-007 3029084-3057429 nonsense_mediated_decay
  ENST00000465207 CARS-009 3038131-3040088 retained_intron
  ENST00000465240 CARS-010 3019190-3029057 processed_transcript
  ENST00000465331 CARS-008 3040524-3057437 processed_transcript
  ENST00000466442 CARS-005 3000930-3008897 retained_intron
  ENST00000470221 CARS-006 3000930-3009533 processed_transcript
  ENST00000484484 CARS-011 3000929-3007010 retained_intron
  ENST00000524825 CARS-015 3039194-3057441 processed_transcript
  ENST00000526890 CARS-014 3000930-3057380 retained_intron
  ENST00000527330 CARS-012 3039215-3057416 nonsense_mediated_decay
  ENST00000529772 CARS-016 3000930-3057402 protein_coding
  ENST00000531387 CARS-003 3000922-3057437 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000278224ENST00000380525ENST00000397111ENST00000466442ENST00000484484ENST00000526890ENST00000529772ENST00000531387
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000278224 8.418±0.00 15.045±0.00 8.123±5.66 13.299±0.00 2.127±0.48 1.399±0.81 6.647±0.00 2.490±1.66 4.840±3.46 16.785±0.00 10.501±5.92 8.053±0.70 6.196±1.77
ENST00000380525 2.853±0.00 N/A N/A N/A 4.364±0.00 1.442±0.00 N/A N/A 4.490±0.00 6.214±0.00 1.397±0.00 3.562±0.00 3.585±0.49
ENST00000397111 N/A N/A 2.310±0.00 7.267±0.00 3.450±0.00 N/A 2.567±0.29 3.873±0.00 2.668±0.00 6.683±6.16 9.346±5.62 6.715±1.71 7.633±1.83
ENST00000466442 N/A N/A N/A 0.911±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000484484 N/A 10.151±0.00 8.850±0.00 N/A N/A N/A 4.776±0.00 3.501±0.00 5.084±0.00 N/A 8.074±2.97 N/A 6.036±0.00
ENST00000526890 N/A 2.008±0.00 2.277±0.00 N/A N/A 0.344±0.00 N/A N/A N/A N/A N/A N/A 2.312±0.00
ENST00000529772 N/A N/A N/A N/A N/A N/A N/A 0.661±0.00 N/A N/A N/A N/A N/A
ENST00000531387 N/A N/A N/A 0.743±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006OC CIL_0006OC_0002 CGP 11:2944431-3057613

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000049 IDA tRNA binding
GO:0000166 IEA nucleotide binding
GO:0004812 IEA aminoacyl-tRNA ligase activity
GO:0004817 IDA:IEA cysteine-tRNA ligase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005829 IBA cytosol
GO:0006418 TAS:IEA tRNA aminoacylation for protein translation
GO:0006423 IDA:IEA cysteinyl-tRNA aminoacylation
GO:0010467 TAS gene expression
GO:0042803 IDA protein homodimerization activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036164 cars cysteinyl-tRNA synthetase protein_coding Danio_rerio
ENSMUSG00000010755 Cars cysteinyl-tRNA synthetase protein_coding Mus_musculus

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