C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: von Willebrand factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110799 VWF 9606 - 12:5948874-6124770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261405 VWF-002 5948874-6124675 protein_coding
  ENST00000321023 VWF-001 6095283-6124670 nonsense_mediated_decay
  ENST00000538563 VWF-006 6121177-6124670 nonsense_mediated_decay
  ENST00000538635 VWF-003 5993880-6124770 processed_transcript
  ENST00000539641 VWF-007 6019528-6021926 processed_transcript
  ENST00000540192 VWF-005 6122724-6124665 processed_transcript
  ENST00000545906 VWF-004 6122706-6124674 processed_transcript
  ENST00000612016 VWF-009 5951873-5953890 retained_intron
  ENST00000621700 VWF-010 5952268-5968214 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261405ENST00000621700
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261405 323.538±0.00 40.349±0.00 0.904±0.00 12.693±11.29 40.705±31.45 64.981±61.76 36.637±29.35 1.113±0.00 4.503±4.32 32.031±1.77 9.373±0.03 7.188±4.29 20.627±8.88 41.003±0.00
ENST00000621700 N/A N/A N/A 2.102±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 IEA liver development
GO:0001890 IEA placenta development
GO:0001948 IDA glycoprotein binding
GO:0002020 IPI protease binding
GO:0002576 TAS platelet degranulation
GO:0005178 IPI integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005518 IDA collagen binding
GO:0005576 IDA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005783 IDA endoplasmic reticulum
GO:0007155 IDA:IEA cell adhesion
GO:0007596 IMP:IEA blood coagulation
GO:0007597 TAS blood coagulation, intrinsic pathway
GO:0007599 IMP hemostasis
GO:0009611 TAS response to wounding
GO:0009897 IEA external side of plasma membrane
GO:0019865 IDA immunoglobulin binding
GO:0030168 NAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0031012 IDA extracellular matrix
GO:0031091 NAS platelet alpha granule
GO:0031093 TAS platelet alpha granule lumen
GO:0031589 IDA cell-substrate adhesion
GO:0033093 IDA Weibel-Palade body
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0047485 IPI protein N-terminus binding
GO:0051087 IDA chaperone binding
GO:0051260 IDA protein homooligomerization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077231 vwf von Willebrand factor protein_coding Danio_rerio
ENSMUSG00000001930 Vwf Von Willebrand factor homolog protein_coding Mus_musculus

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