C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110801 PSMD9 9606 + 12:121888731-121918297 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261817 PSMD9-001 121888771-121917863 protein_coding
  ENST00000361485 PSMD9-010 121914218-121916643 retained_intron
  ENST00000535293 PSMD9-009 121893817-121916584 nonsense_mediated_decay
  ENST00000537407 PSMD9-002 121888732-121916644 nonsense_mediated_decay
  ENST00000538613 PSMD9-005 121888784-121899853 protein_coding
  ENST00000540962 PSMD9-006 121888762-121916549 nonsense_mediated_decay
  ENST00000541212 PSMD9-003 121888731-121918297 protein_coding
  ENST00000542602 PSMD9-011 121888786-121916399 protein_coding
  ENST00000543699 PSMD9-004 121888845-121916584 nonsense_mediated_decay
  ENST00000544254 PSMD9-007 121902048-121916615 retained_intron
  ENST00000544724 PSMD9-008 121897271-121916568 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261817ENST00000361485ENST00000537407ENST00000538613ENST00000540962ENST00000542602ENST00000543699ENST00000544254
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261817 N/A N/A 1.529±0.00 4.120±0.00 3.133±0.00 N/A N/A N/A N/A N/A N/A 3.788±0.97 2.161±0.00 N/A
ENST00000361485 N/A N/A N/A N/A N/A 0.894±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000537407 7.615±0.00 22.007±0.00 N/A 2.327±0.00 12.082±0.00 7.079±3.38 5.478±4.70 17.762±12.46 6.522±2.87 9.173±0.00 2.215±0.30 25.548±20.44 20.200±7.65 25.712±0.00
ENST00000538613 14.316±0.00 N/A N/A N/A 24.528±0.00 N/A 1.502±0.00 N/A N/A N/A 11.166±0.00 N/A N/A N/A
ENST00000540962 N/A N/A N/A N/A N/A N/A 9.157±0.00 N/A N/A N/A 6.467±0.00 6.405±0.00 N/A N/A
ENST00000542602 9.591±0.00 N/A N/A 5.017±0.00 N/A N/A N/A N/A 4.061±0.00 N/A 5.294±0.00 N/A N/A N/A
ENST00000543699 8.156±0.00 17.623±0.00 N/A 12.392±0.00 6.389±4.24 16.139±0.00 0.582±0.00 26.473±0.00 13.499±0.00 6.657±4.46 4.364±0.00 16.096±1.00 11.968±3.40 N/A
ENST00000544254 N/A N/A N/A N/A N/A N/A 0.408±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ZH CIL_0002ZH_0001 CGP 12:121839527-121918297

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0003713 ISS transcription coactivator activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005838 NAS proteasome regulatory particle
GO:0006511 NAS ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008540 IDA proteasome regulatory particle, base subcomplex
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032024 ISS positive regulation of insulin secretion
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043425 ISS bHLH transcription factor binding
GO:0044281 TAS small molecule metabolic process
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046676 ISS negative regulation of insulin secretion
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070682 IMP proteasome regulatory particle assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006300 psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 protein_coding Danio_rerio
ENSMUSG00000029440 Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 protein_coding Mus_musculus

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