C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cut-like homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111249 CUX2 9606 + 12:111034024-111350554 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261726 CUX2-001 111034024-111350554 protein_coding
  ENST00000397643 CUX2-002 111099446-111295346 protein_coding
  ENST00000551604 CUX2-003 111214301-111270654 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000261726
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000261726 0.011±0.00 0.033±0.00 0.030±0.00 1.841±0.27 0.049±0.03 0.090±0.00 0.020±0.00 0.016±0.00 0.047±0.00 0.016±0.00 0.023±0.01 0.044±0.01 0.449±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YU CIL_0008YU_0001 VISTA 12:110628804-111231731
CIL_000903 CIL_000903_0001 VISTA 12:110757593-111358448
CIL_0008TJ CIL_0008TJ_0001 VISTA 12:110911282-111513646

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 ISS RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677 IEA DNA binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007614 ISS short-term memory
GO:0010628 ISS positive regulation of gene expression
GO:0043565 IDA sequence-specific DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0050775 ISS positive regulation of dendrite morphogenesis
GO:0050890 IMP cognition
GO:0051965 ISS positive regulation of synapse assembly
GO:0061003 ISS positive regulation of dendritic spine morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0071310 IEA cellular response to organic substance
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086345 cux2b cut-like homeobox 2b protein_coding Danio_rerio
ENSMUSG00000042589 Cux2 cut-like homeobox 2 protein_coding Mus_musculus

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