C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cut-like homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042589 Cux2 10090 - 5:121858387-122050102 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086317 Cux2-002 121860216-122047825 protein_coding
  ENSMUST00000111752 Cux2-001 121858387-122049851 protein_coding
  ENSMUST00000125267 Cux2-005 121924896-122047891 processed_transcript
  ENSMUST00000133760 Cux2-008 121879815-121915072 processed_transcript
  ENSMUST00000134326 Cux2-006 121887421-122002344 protein_coding
  ENSMUST00000144069 Cux2-007 121879821-121895381 processed_transcript
  ENSMUST00000154139 Cux2-004 121884754-122050102 protein_coding
  ENSMUST00000155396 Cux2-003 121895409-121916734 processed_transcript
  ENSMUST00000156942 Cux2-009 121873089-121874198 protein_coding
  ENSMUST00000168288 Cux2-201 121860308-121924921 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086317ENSMUST00000111752ENSMUST00000133760ENSMUST00000154139ENSMUST00000168288
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086317 0.123±0.00 1.696±0.43 N/A N/A N/A N/A 0.682±0.00 0.161±0.04 0.453±0.00 0.227±0.00 0.093±0.00 0.537±0.26 N/A N/A
ENSMUST00000111752 0.070±0.00 1.646±0.68 0.455±0.19 7.413±3.26 0.048±0.00 0.054±0.00 0.510±0.09 0.149±0.04 1.442±0.00 0.213±0.03 0.160±0.00 0.359±0.19 0.217±0.13 N/A
ENSMUST00000133760 N/A N/A N/A N/A 0.347±0.00 N/A N/A N/A N/A N/A 0.278±0.00 1.241±0.39 N/A 1.970±0.00
ENSMUST00000154139 N/A N/A N/A N/A N/A 0.805±0.00 N/A N/A N/A N/A 0.480±0.00 N/A N/A N/A
ENSMUST00000168288 0.208±0.04 4.183±0.76 0.656±0.09 5.226±0.14 0.056±0.04 N/A 1.210±0.25 0.166±0.01 2.002±1.45 0.630±0.11 0.151±0.08 0.591±0.24 0.298±0.00 1.018±0.59

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TJ CIL_0008TJ_0002 VISTA 5:121625608-122227679
CIL_000903 CIL_000903_0002 VISTA 5:121732502-122333355
CIL_0008YU CIL_0008YU_0002 VISTA 5:121792218-122394768
CIL_0001G2 CIL_0001G2_0002 CGP 5:121858387-122113472

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IMP RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677 IDA DNA binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007614 IMP short-term memory
GO:0010628 IMP positive regulation of gene expression
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0050775 IMP positive regulation of dendrite morphogenesis
GO:0050890 IEA cognition
GO:0051965 IMP positive regulation of synapse assembly
GO:0061003 IMP positive regulation of dendritic spine morphogenesis
GO:0070062 IEA extracellular vesicular exosome
GO:0071310 IDA cellular response to organic substance
GO:2000463 IMP positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086345 cux2b cut-like homeobox 2b protein_coding Danio_rerio
ENSG00000111249 CUX2 cut-like homeobox 2 protein_coding Homo_sapiens

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