C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111728 ST8SIA1 9606 - 12:22063773-22437041 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261197 ST8SIA1-007 22200999-22334714 nonsense_mediated_decay
  ENST00000381424 ST8SIA1-003 22325099-22334671 protein_coding
  ENST00000396037 ST8SIA1-001 22193391-22334714 protein_coding
  ENST00000404299 ST8SIA1-002 22324379-22334700 protein_coding
  ENST00000508924 ST8SIA1-009 22201661-22268605 processed_transcript
  ENST00000536535 ST8SIA1-015 22063773-22070613 processed_transcript
  ENST00000536558 ST8SIA1-004 22324412-22437041 processed_transcript
  ENST00000537795 ST8SIA1-014 22107159-22118489 processed_transcript
  ENST00000538256 ST8SIA1-012 22223272-22249046 protein_coding
  ENST00000540824 ST8SIA1-006 22201904-22336200 protein_coding
  ENST00000541868 ST8SIA1-011 22248826-22334163 protein_coding
  ENST00000544732 ST8SIA1-010 22066419-22250787 processed_transcript
  ENST00000545185 ST8SIA1-005 22354203-22376943 processed_transcript
  ENST00000545494 ST8SIA1-008 22201468-22268613 processed_transcript
  ENST00000545524 ST8SIA1-013 22107275-22287194 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261197ENST00000396037ENST00000536558ENST00000540824ENST00000541868ENST00000545185ENST00000545494
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261197 N/A 1.495±0.00 N/A 3.717±0.00 1.036±0.00 1.101±0.65 0.286±0.05 0.185±0.00 0.849±0.83 2.100±1.74 0.088±0.00 0.694±0.50 0.219±0.08 1.201±0.06
ENST00000396037 N/A 0.335±0.00 0.026±0.00 1.176±0.00 0.202±0.00 0.385±0.00 0.062±0.00 0.062±0.00 0.014±0.00 0.206±0.09 N/A 0.197±0.00 0.034±0.00 0.051±0.00
ENST00000536558 0.034±0.00 N/A 0.028±0.00 N/A 0.179±0.00 N/A N/A N/A N/A N/A N/A 0.095±0.00 N/A N/A
ENST00000540824 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.559±0.00 N/A
ENST00000541868 N/A N/A N/A N/A N/A N/A N/A 0.080±0.00 N/A N/A 1.004±0.00 N/A N/A N/A
ENST00000545185 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.063±0.00
ENST00000545494 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.161±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090B CIL_00090B_0001 VISTA 12:21591137-22192666
CIL_0005PR CIL_0005PR_0001 CGP 12:21797401-22065674
CIL_0005PQ CIL_0005PQ_0001 CGP 12:22063773-22544546

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003828 IEA alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0005794 IEA Golgi apparatus
GO:0005975 TAS carbohydrate metabolic process
GO:0006486 IEA protein glycosylation
GO:0006688 TAS glycosphingolipid biosynthetic process
GO:0008284 IEA positive regulation of cell proliferation
GO:0008373 TAS sialyltransferase activity
GO:0016021 TAS integral component of membrane
GO:0030173 IEA integral component of Golgi membrane
GO:0034605 IEA cellular response to heat
GO:0097503 IEA sialylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055728 st8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 protein_coding Danio_rerio
ENSDARG00000074347 st8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 protein_coding Danio_rerio
ENSMUSG00000030283 St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 protein_coding Mus_musculus

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