C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activation-induced cytidine deaminase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111732 AICDA 9606 - 12:8602166-8612871 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229335 AICDA-001 8602166-8612871 protein_coding
  ENST00000537228 AICDA-005 8604284-8612867 protein_coding
  ENST00000543081 AICDA-004 8603686-8607016 protein_coding
  ENST00000544516 AICDA-003 8604284-8607016 protein_coding
  ENST00000545512 AICDA-002 8604285-8607016 protein_coding
  ENST00000545576 AICDA-006 8604284-8612801 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000229335ENST00000543081ENST00000545512ENST00000545576
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000229335 0.024±0.00 0.081±0.00 0.067±0.00 0.039±0.00 0.053±0.00 0.086±0.00 0.017±0.00 N/A 0.009±0.00 N/A 0.062±0.00
ENST00000543081 N/A N/A N/A N/A N/A N/A N/A 0.592±0.00 N/A 0.054±0.00 N/A
ENST00000545512 N/A N/A N/A N/A N/A N/A N/A 0.197±0.00 N/A N/A N/A
ENST00000545576 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.042±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HL CIL_0008HL_0001 VISTA 12:8543390-9149656
CIL_0003ND CIL_0003ND_0002 CGP 12:8602166-8662888

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000178 IDA exosome (RNase complex)
GO:0003824 IEA catalytic activity
GO:0004126 NAS cytidine deaminase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006397 IEA mRNA processing
GO:0008270 IEA zinc ion binding
GO:0009972 IEA cytidine deamination
GO:0016445 IDA somatic diversification of immunoglobulins
GO:0016446 IMP somatic hypermutation of immunoglobulin genes
GO:0016814 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO:0030183 NAS B cell differentiation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0045190 IEA isotype switching
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0080111 IDA DNA demethylation
GO:0090310 IDA negative regulation of methylation-dependent chromatin silencing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015734 aicda activation-induced cytidine deaminase protein_coding Danio_rerio
ENSMUSG00000040627 Aicda activation-induced cytidine deaminase protein_coding Mus_musculus

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