C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activation-induced cytidine deaminase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040627 Aicda 10090 + 6:122553801-122564180 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043301 Aicda-001 122553801-122564180 protein_coding
  ENSMUST00000160685 Aicda-002 122560485-122563076 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENSMUST00000043301ENSMUST00000160685
Transcript ID Adipose Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043301 N/A 0.003±0.00 0.024±0.00 0.256±0.11 0.166±0.08 0.015±0.00 0.005±0.00 0.088±0.00 0.243±0.00 0.376±0.17 0.025±0.00 N/A
ENSMUST00000160685 0.055±0.03 0.007±0.00 0.139±0.07 0.096±0.02 0.144±0.06 N/A 0.047±0.01 0.042±0.00 N/A 0.169±0.09 0.039±0.03 0.028±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HL CIL_0008HL_0002 VISTA 6:122092605-122696323

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000178 IEA exosome (RNase complex)
GO:0004126 IDA cytidine deaminase activity
GO:0005515 IPI protein binding
GO:0005634 IC:ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006397 IEA mRNA processing
GO:0008270 IEA zinc ion binding
GO:0009972 IDA:IMP cytidine deamination
GO:0016445 IEA somatic diversification of immunoglobulins
GO:0016446 ISS somatic hypermutation of immunoglobulin genes
GO:0031625 IEA ubiquitin protein ligase binding
GO:0045190 IMP isotype switching
GO:0071222 IMP cellular response to lipopolysaccharide
GO:0080111 ISS DNA demethylation
GO:0090310 ISS negative regulation of methylation-dependent chromatin silencing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015734 aicda activation-induced cytidine deaminase protein_coding Danio_rerio
ENSG00000111732 AICDA activation-induced cytidine deaminase protein_coding Homo_sapiens

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