C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activation-induced cytidine deaminase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000537228 AICDA-005 ENSG00000111732 9606 - 12:8604284-8612867 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HL CIL_0008HL_0001 VISTA 12:8543390-9149656
CIL_0003ND CIL_0003ND_0002 CGP 12:8602166-8662888

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000178 IDA exosome (RNase complex)
GO:0003824 IEA catalytic activity
GO:0004126 NAS cytidine deaminase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006397 IEA mRNA processing
GO:0008270 IEA zinc ion binding
GO:0016445 IDA somatic diversification of immunoglobulins
GO:0016446 IMP somatic hypermutation of immunoglobulin genes
GO:0016814 IEA hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO:0030183 NAS B cell differentiation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0080111 IDA DNA demethylation
GO:0090310 IDA negative regulation of methylation-dependent chromatin silencing

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000043301 Aicda-001 protein_coding Mus_musculus 0 510
ENSMUST00000160685 Aicda-002 protein_coding Mus_musculus 0 337

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