C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RIC8 guanine nucleotide exchange factor B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111785 RIC8B 9606 + 12:106774595-106889316 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355478 RIC8B-002 106774671-106887284 protein_coding
  ENST00000392837 RIC8B-001 106774595-106889316 protein_coding
  ENST00000392839 RIC8B-006 106774640-106886786 protein_coding
  ENST00000462949 RIC8B-003 106774714-106887290 nonsense_mediated_decay
  ENST00000470628 RIC8B-005 106774746-106871505 retained_intron
  ENST00000470960 RIC8B-004 106822258-106887282 nonsense_mediated_decay
  ENST00000546449 RIC8B-010 106870823-106886360 nonsense_mediated_decay
  ENST00000548914 RIC8B-012 106774663-106860316 protein_coding
  ENST00000549643 RIC8B-008 106774682-106886181 protein_coding
  ENST00000550215 RIC8B-007 106774621-106814870 nonsense_mediated_decay
  ENST00000551756 RIC8B-011 106879728-106886250 retained_intron
  ENST00000552619 RIC8B-009 106774682-106814966 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355478ENST00000392837ENST00000392839ENST00000462949ENST00000470628ENST00000470960
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355478 N/A N/A N/A N/A N/A N/A 2.055±0.00 N/A 0.703±0.00 N/A N/A N/A N/A
ENST00000392837 0.561±0.00 0.820±0.00 2.647±0.00 1.192±0.00 0.749±0.34 3.048±0.00 0.398±0.00 1.145±0.65 0.321±0.00 N/A 1.114±0.46 0.957±0.23 2.175±0.40
ENST00000392839 N/A N/A N/A 2.072±0.00 1.560±0.40 3.985±0.00 2.817±0.00 N/A N/A 1.373±0.03 1.097±0.30 1.347±0.00 N/A
ENST00000462949 0.711±0.00 N/A N/A N/A 1.659±0.00 N/A N/A N/A N/A 0.880±0.00 1.169±0.00 0.854±0.13 1.197±0.00
ENST00000470628 N/A N/A 2.856±0.00 1.712±0.00 0.990±0.00 1.556±0.00 N/A N/A 1.858±0.00 N/A 2.054±0.00 N/A N/A
ENST00000470960 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.065±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001MF CIL_0001MF_0001 CGP 12:106582907-106889316

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001965 IDA G-protein alpha-subunit binding
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0008277 IDA regulation of G-protein coupled receptor protein signaling pathway
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005972 ric8b resistance to inhibitors of cholinesterase 8 homolog B protein_coding Danio_rerio
ENSMUSG00000035620 Ric8b resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) protein_coding Mus_musculus

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