C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113300 CNOT6 9606 + 5:180494412-180578405 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261951 CNOT6-201 180494417-180578353 protein_coding
  ENST00000393356 CNOT6-001 180494433-180578405 protein_coding
  ENST00000502447 CNOT6-003 180494707-180564682 processed_transcript
  ENST00000504343 CNOT6-004 180529275-180567968 protein_coding
  ENST00000507016 CNOT6-005 180494447-180549995 processed_transcript
  ENST00000510148 CNOT6-006 180494412-180495755 processed_transcript
  ENST00000618123 CNOT6-202 180494507-180578349 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261951ENST00000393356ENST00000504343ENST00000618123
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261951 4.319±0.00 2.075±0.00 N/A 1.366±1.16 3.072±0.00 2.161±1.04 1.492±1.08 4.367±0.00 0.660±0.00 2.569±0.21 N/A 2.625±1.34 3.186±1.28 5.424±1.04
ENST00000393356 N/A N/A N/A 1.198±0.00 N/A 0.990±0.00 N/A N/A N/A N/A N/A 0.648±0.07 0.370±0.00 N/A
ENST00000504343 N/A N/A N/A N/A N/A N/A N/A 2.278±0.00 N/A N/A 1.086±0.00 3.263±0.00 6.534±0.00 8.149±0.00
ENST00000618123 N/A N/A 2.302±0.00 N/A 4.037±0.00 N/A 0.427±0.00 N/A 0.403±0.00 1.312±0.53 N/A 1.071±0.16 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0003723 IEA RNA binding
GO:0004532 IDA exoribonuclease activity
GO:0004535 IDA poly(A)-specific ribonuclease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0008284 IMP positive regulation of cell proliferation
GO:0010467 TAS gene expression
GO:0010606 IMP positive regulation of cytoplasmic mRNA processing body assembly
GO:0016020 IDA membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0030014 IDA CCR4-NOT complex
GO:0035195 TAS gene silencing by miRNA
GO:0043928 IDA exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0046872 IEA metal ion binding
GO:0070966 IMP nuclear-transcribed mRNA catabolic process, no-go decay
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:2000327 IDA positive regulation of ligand-dependent nuclear receptor transcription coactivator activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008255 cnot6 CCR4-NOT transcription complex, subunit 6 protein_coding Danio_rerio
ENSDARG00000022001 CNOT6 (2 of 2) CCR4-NOT transcription complex, subunit 6 protein_coding Danio_rerio
ENSMUSG00000020362 Cnot6 CCR4-NOT transcription complex, subunit 6 protein_coding Mus_musculus

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