C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020362 Cnot6 10090 - 11:49671503-49712723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020624 Cnot6-201 49674713-49712710 protein_coding
  ENSMUST00000109183 Cnot6-002 49674698-49702632 processed_transcript
  ENSMUST00000145353 Cnot6-001 49671503-49712723 protein_coding
  ENSMUST00000145424 Cnot6-003 49677384-49680401 processed_transcript
  ENSMUST00000151090 Cnot6-004 49681153-49682725 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020624ENSMUST00000109183ENSMUST00000145353ENSMUST00000151090
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020624 3.496±1.45 4.738±1.69 N/A N/A 4.394±1.50 3.356±1.09 1.175±0.00 2.702±0.39 5.244±2.81 4.944±0.66 N/A 12.591±3.76 9.963±4.55 5.538±2.17
ENSMUST00000109183 N/A N/A N/A 2.685±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 13.125±5.22 3.076±0.00
ENSMUST00000145353 4.487±3.23 2.298±0.59 9.147±4.23 14.150±8.91 4.141±1.73 3.517±0.79 1.637±0.69 4.824±1.43 5.534±4.02 9.056±2.08 0.842±0.54 10.319±3.57 7.242±3.63 3.951±1.92
ENSMUST00000151090 N/A N/A N/A 8.462±0.00 N/A N/A N/A N/A N/A N/A N/A 43.934±0.00 22.150±6.89 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0004532 ISS exoribonuclease activity
GO:0004535 ISS poly(A)-specific ribonuclease activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0008284 IEA positive regulation of cell proliferation
GO:0010606 IEA positive regulation of cytoplasmic mRNA processing body assembly
GO:0016020 IEA membrane
GO:0030014 ISS CCR4-NOT complex
GO:0031047 IEA gene silencing by RNA
GO:0043928 ISS exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0046872 IEA metal ion binding
GO:0070966 ISS nuclear-transcribed mRNA catabolic process, no-go decay
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:2000327 ISS positive regulation of ligand-dependent nuclear receptor transcription coactivator activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008255 cnot6 CCR4-NOT transcription complex, subunit 6 protein_coding Danio_rerio
ENSDARG00000022001 CNOT6 (2 of 2) CCR4-NOT transcription complex, subunit 6 protein_coding Danio_rerio
ENSG00000113300 CNOT6 CCR4-NOT transcription complex, subunit 6 protein_coding Homo_sapiens

Loading