C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Ras protein-specific guanine nucleotide-releasing factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113319 RASGRF2 9606 + 5:80960672-81230156 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265080 RASGRF2-001 80960672-81230156 protein_coding
  ENST00000502677 RASGRF2-005 81070024-81088564 processed_transcript
  ENST00000503795 RASGRF2-002 80960689-81225812 nonsense_mediated_decay
  ENST00000512186 RASGRF2-004 81092916-81096506 processed_transcript
  ENST00000514946 RASGRF2-006 81019407-81073222 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265080ENST00000502677ENST00000503795
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265080 5.264±0.00 0.789±0.00 N/A 11.708±0.00 6.330±0.00 1.026±0.76 0.787±0.33 0.295±0.00 0.197±0.10 1.413±0.90 0.455±0.00 1.311±0.85 2.750±0.56 0.358±0.00
ENST00000502677 N/A N/A N/A N/A 2.868±1.81 N/A N/A 0.155±0.00 N/A 3.106±0.00 N/A 1.855±0.77 N/A N/A
ENST00000503795 N/A N/A 1.407±0.00 N/A N/A N/A 0.570±0.00 0.082±0.00 0.432±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TH CIL_0005TH_0002 CGP 5:80960672-81266397

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005622 IEA intracellular
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007268 TAS synaptic transmission
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS:IEA regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway
GO:2000310 IEA regulation of N-methyl-D-aspartate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002816 rasgrf2b Ras protein-specific guanine nucleotide-releasing factor 2b protein_coding Danio_rerio
ENSDARG00000075054 RASGRF2 (2 of 2) Ras protein-specific guanine nucleotide-releasing factor 2 protein_coding Danio_rerio
ENSMUSG00000021708 Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 protein_coding Mus_musculus

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