C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Ras protein-specific guanine nucleotide-releasing factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265080 RASGRF2-001 ENSG00000113319 9606 + 5:80960672-81230156 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265080
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265080 5.264±0.00 0.789±0.00 11.708±0.00 6.330±0.00 1.026±0.76 0.787±0.33 0.295±0.00 0.197±0.10 1.413±0.90 0.455±0.00 1.311±0.85 2.750±0.56 0.358±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TH CIL_0005TH_0002 CGP 5:80960672-81266397

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005622 IEA intracellular
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007268 TAS synaptic transmission
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS:IEA regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway
GO:2000310 IEA regulation of N-methyl-D-aspartate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000099326 Rasgrf2-201 protein_coding Mus_musculus 0 1679
ENSMUST00000151408 Rasgrf2-001 protein_coding Mus_musculus 0 1465
ENSMUST00000146492 Rasgrf2-003 protein_coding Mus_musculus 0 1458
ENSDART00000083350 rasgrf2b-001 protein_coding Danio_rerio 0 712
ENSMUST00000149630 Rasgrf2-004 protein_coding Mus_musculus 0 651
ENSMUST00000142378 Rasgrf2-002 protein_coding Mus_musculus 0 647

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