C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 1 (acidic)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113578 FGF1 9606 - 5:142592178-142698070 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000337706 FGF1-002 142594752-142686385 protein_coding
  ENST00000359370 FGF1-001 142592178-142621342 protein_coding
  ENST00000360966 FGF1-007 142595088-142686051 protein_coding
  ENST00000378046 FGF1-008 142593369-142685672 protein_coding
  ENST00000394496 FGF1-004 142600800-142644201 protein_coding
  ENST00000407758 FGF1-009 142595231-142698021 protein_coding
  ENST00000411960 FGF1-013 142614005-142686066 protein_coding
  ENST00000419524 FGF1-010 142595243-142698046 protein_coding
  ENST00000441680 FGF1-006 142595243-142698046 protein_coding
  ENST00000489937 FGF1-003 142595161-142698052 retained_intron
  ENST00000494344 FGF1-012 142595231-142698052 retained_intron
  ENST00000494579 FGF1-011 142595243-142698052 processed_transcript
  ENST00000610990 FGF1-201 142592179-142644301 protein_coding
  ENST00000612258 FGF1-202 142592179-142686495 protein_coding
  ENST00000619447 FGF1-203 142592179-142685703 protein_coding
  ENST00000621536 FGF1-204 142592179-142698070 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000337706ENST00000359370ENST00000378046ENST00000419524ENST00000441680ENST00000494579ENST00000612258ENST00000621536
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000337706 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.554±0.00 N/A
ENST00000359370 0.457±0.00 0.092±0.00 N/A 29.640±0.00 2.970±0.00 0.084±0.00 N/A 17.888±0.00 0.022±0.00 1.046±0.00 N/A 0.167±0.16 0.349±0.27 0.572±0.00
ENST00000378046 N/A N/A N/A N/A 0.434±0.00 0.220±0.00 N/A N/A 0.016±0.00 N/A 0.288±0.00 0.096±0.00 0.296±0.15 0.137±0.00
ENST00000419524 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.384±0.00 N/A N/A N/A N/A
ENST00000441680 N/A N/A 4.896±0.00 N/A N/A N/A 1.592±0.00 N/A N/A 0.347±0.00 N/A N/A N/A N/A
ENST00000494579 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.207±0.00 N/A N/A
ENST00000612258 0.253±0.00 N/A N/A 11.514±4.76 N/A 0.218±0.00 N/A N/A N/A N/A N/A 0.244±0.00 0.347±0.00 N/A
ENST00000621536 0.118±0.00 N/A 1.893±0.00 N/A 2.769±0.00 N/A 1.620±1.32 7.894±0.00 N/A N/A N/A 0.140±0.00 N/A 0.074±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007W6 CIL_0007W6_0001 VISTA 5:142250490-142852711

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001759 IEA organ induction
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0005104 IEA:IPI fibroblast growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 IDA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0007165 NAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0008083 IDA:IEA growth factor activity
GO:0008201 IDA heparin binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 IEA:IPI fibroblast growth factor receptor signaling pathway
GO:0009653 TAS anatomical structure morphogenesis
GO:0030154 IEA cell differentiation
GO:0030324 IEA lung development
GO:0030335 IDA positive regulation of cell migration
GO:0030544 IEA Hsp70 protein binding
GO:0034605 IDA cellular response to heat
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0044548 IPI S100 protein binding
GO:0045087 TAS innate immune response
GO:0045542 IDA positive regulation of cholesterol biosynthetic process
GO:0045766 IDA positive regulation of angiogenesis
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0051781 IDA positive regulation of cell division
GO:0060681 IDA branch elongation involved in ureteric bud branching
GO:0072163 IDA mesonephric epithelium development
GO:1902533 IDA positive regulation of intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000036585 Fgf1 fibroblast growth factor 1 protein_coding Mus_musculus

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