C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036585 Fgf1 10090 - 18:38838673-38929404 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000040647 Fgf1-001 38838673-38918771 protein_coding
  ENSMUST00000115582 Fgf1-002 38840177-38866747 protein_coding
  ENSMUST00000117566 Fgf1-007 38841907-38858748 protein_coding
  ENSMUST00000131348 Fgf1-003 38838675-38929404 nonsense_mediated_decay
  ENSMUST00000134864 Fgf1-006 38858568-38929157 protein_coding
  ENSMUST00000139972 Fgf1-004 38847084-38866132 protein_coding
  ENSMUST00000147607 Fgf1-005 38847125-38858861 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040647ENSMUST00000115582ENSMUST00000117566ENSMUST00000134864ENSMUST00000147607
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040647 3.225±0.01 3.361±2.07 1.922±0.00 2.569±2.53 1.396±0.45 4.170±0.00 11.585±1.90 5.992±1.81 1.020±0.96 44.149±0.89 2.021±1.29 2.203±1.04 0.396±0.47 0.137±0.12
ENSMUST00000115582 N/A N/A 1.515±0.00 N/A N/A N/A N/A N/A 1.196±0.24 N/A N/A N/A 2.121±1.16 0.078±0.02
ENSMUST00000117566 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.546±0.00
ENSMUST00000134864 N/A 6.575±2.41 N/A 0.106±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000147607 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.381±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007W6 CIL_0007W6_0002 VISTA 18:38503792-39105763

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001759 IDA organ induction
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0005104 IEA:ISS fibroblast growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 IDA:ISS extracellular region
GO:0005578 IDA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005829 ISS cytosol
GO:0008083 ISS growth factor activity
GO:0008201 ISS heparin binding
GO:0008284 ISS positive regulation of cell proliferation
GO:0008543 IEA:ISS fibroblast growth factor receptor signaling pathway
GO:0030324 IDA lung development
GO:0030335 ISS positive regulation of cell migration
GO:0030544 IEA Hsp70 protein binding
GO:0034605 ISS cellular response to heat
GO:0044548 ISS S100 protein binding
GO:0045542 ISS positive regulation of cholesterol biosynthetic process
GO:0045766 ISS positive regulation of angiogenesis
GO:0045893 TAS positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0050679 IDA positive regulation of epithelial cell proliferation
GO:0051781 ISS positive regulation of cell division
GO:0060038 TAS cardiac muscle cell proliferation
GO:0060681 ISS branch elongation involved in ureteric bud branching
GO:0060979 TAS vasculogenesis involved in coronary vascular morphogenesis
GO:0072163 ISS mesonephric epithelium development
GO:1902533 ISS positive regulation of intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000113578 FGF1 fibroblast growth factor 1 (acidic) protein_coding Homo_sapiens

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