C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leukemia inhibitory factor receptor alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113594 LIFR 9606 - 5:38474963-38608354 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263409 LIFR-001 38474963-38595404 protein_coding
  ENST00000453190 LIFR-003 38480968-38556646 protein_coding
  ENST00000503088 LIFR-002 38490620-38595404 processed_transcript
  ENST00000506003 LIFR-007 38485937-38502675 nonsense_mediated_decay
  ENST00000506990 LIFR-004 38527175-38556636 protein_coding
  ENST00000507786 LIFR-009 38594971-38608354 processed_transcript
  ENST00000508477 LIFR-008 38485597-38489245 retained_intron
  ENST00000511561 LIFR-005 38528759-38557465 protein_coding
  ENST00000512723 LIFR-006 38528672-38530917 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263409ENST00000453190ENST00000503088
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263409 1.399±0.00 23.733±0.00 N/A 7.124±0.00 6.036±2.18 2.374±0.00 3.888±2.02 7.776±3.25 1.998±0.44 10.139±0.49 N/A 2.586±2.52 2.181±0.41 8.601±0.00
ENST00000453190 N/A N/A N/A N/A N/A N/A 2.816±0.00 N/A 3.194±0.00 7.968±0.00 1.603±0.00 1.949±0.00 N/A N/A
ENST00000503088 N/A N/A 3.120±0.00 N/A N/A N/A N/A N/A 4.715±0.00 N/A 2.335±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004897 IDA ciliary neurotrophic factor receptor activity
GO:0004923 IDA leukemia inhibitory factor receptor activity
GO:0004924 IDA oncostatin-M receptor activity
GO:0005127 IPI ciliary neurotrophic factor receptor binding
GO:0005515 IEA protein binding
GO:0005887 TAS integral component of plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019838 IPI growth factor binding
GO:0034097 IDA response to cytokine
GO:0038165 IDA oncostatin-M-mediated signaling pathway
GO:0048861 IDA leukemia inhibitory factor signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0070120 IDA ciliary neurotrophic factor-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039863 lifrb leukemia inhibitory factor receptor alpha b protein_coding Danio_rerio
ENSDARG00000042909 lifra leukemia inhibitory factor receptor alpha a protein_coding Danio_rerio
ENSMUSG00000054263 Lifr leukemia inhibitory factor receptor protein_coding Mus_musculus

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