C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leukemia inhibitory factor receptor alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000453190 LIFR-003 ENSG00000113594 9606 - 5:38480968-38556646 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartLiverLungMuscleOvaryENST00000453190
Transcript ID Heart Liver Lung Muscle Ovary
ENST00000453190 2.816±0.00 3.194±0.00 7.968±0.00 1.603±0.00 1.949±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004897 IDA ciliary neurotrophic factor receptor activity
GO:0004923 IDA leukemia inhibitory factor receptor activity
GO:0004924 IDA oncostatin-M receptor activity
GO:0005127 IPI ciliary neurotrophic factor receptor binding
GO:0005515 IEA protein binding
GO:0005887 TAS integral component of plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019838 IPI growth factor binding
GO:0034097 IDA response to cytokine
GO:0038165 IDA oncostatin-M-mediated signaling pathway
GO:0048861 IDA leukemia inhibitory factor signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0070120 IDA ciliary neurotrophic factor-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000171588 Lifr-203 protein_coding Mus_musculus 0 2379
ENSMUST00000067190 Lifr-201 protein_coding Mus_musculus 0 2348
ENSMUST00000164529 Lifr-202 protein_coding Mus_musculus 0 1125

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