C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leukemia inhibitory factor receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054263 Lifr 10090 + 15:7129559-7197489 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067190 Lifr-201 7129559-7191743 protein_coding
  ENSMUST00000164529 Lifr-202 7129572-7185335 protein_coding
  ENSMUST00000171588 Lifr-203 7154353-7197489 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067190ENSMUST00000164529ENSMUST00000171588
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067190 2.636±0.15 0.844±0.09 N/A N/A 3.341±0.57 0.484±0.12 1.155±0.00 2.028±0.00 7.334±0.00 9.067±2.31 N/A 2.057±0.70 5.319±0.00 0.954±0.20
ENSMUST00000164529 N/A N/A N/A N/A 2.814±0.00 0.591±0.00 N/A 3.543±0.40 11.859±7.85 N/A N/A N/A 11.984±3.07 N/A
ENSMUST00000171588 6.404±0.00 1.800±0.20 5.403±1.03 0.573±0.23 4.212±2.10 0.790±0.13 N/A N/A 10.803±6.65 9.528±0.00 3.576±1.41 3.023±1.45 12.562±4.09 0.379±0.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000688 CIL_000688_0002 CGP 15:6813577-7197489
CIL_0008W3 CIL_0008W3_0002 VISTA 15:7122223-7723664

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004897 IEA ciliary neurotrophic factor receptor activity
GO:0004923 IEA leukemia inhibitory factor receptor activity
GO:0004924 IEA oncostatin-M receptor activity
GO:0005127 IEA ciliary neurotrophic factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005886 IEA plasma membrane
GO:0008284 IGI positive regulation of cell proliferation
GO:0016021 IEA integral component of membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019838 IEA growth factor binding
GO:0034097 IEA response to cytokine
GO:0038165 IEA oncostatin-M-mediated signaling pathway
GO:0048861 IEA leukemia inhibitory factor signaling pathway
GO:0070062 IEA extracellular vesicular exosome
GO:0070120 IEA ciliary neurotrophic factor-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039863 lifrb leukemia inhibitory factor receptor alpha b protein_coding Danio_rerio
ENSDARG00000042909 lifra leukemia inhibitory factor receptor alpha a protein_coding Danio_rerio
ENSG00000113594 LIFR leukemia inhibitory factor receptor alpha protein_coding Homo_sapiens

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