C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: K(lysine) acetyltransferase 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114166 KAT2B 9606 + 3:20040023-20154404 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263754 KAT2B-001 20040023-20154404 protein_coding
  ENST00000426228 KAT2B-002 20040698-20101113 processed_transcript
  ENST00000468111 KAT2B-004 20127478-20146581 retained_intron
  ENST00000468400 KAT2B-005 20148240-20149010 retained_intron
  ENST00000469085 KAT2B-003 20111594-20122795 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263754ENST00000468111
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263754 6.170±0.00 5.164±0.00 2.326±0.00 9.122±4.02 6.065±4.02 4.380±2.49 11.539±8.07 4.015±2.50 4.307±0.74 4.711±1.20 7.075±4.25 3.723±2.25 2.969±0.47 2.653±1.79
ENST00000468111 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.526±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004HU CIL_0004HU_0001 CGP 3:19979961-20154404
CIL_0004HV CIL_0004HV_0001 CGP 3:20040023-20186292

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000123 IEA histone acetyltransferase complex
GO:0000125 NAS PCAF complex
GO:0000776 IEA kinetochore
GO:0003712 IPI transcription cofactor activity
GO:0003713 IDA transcription coactivator activity
GO:0004402 IDA:IEA histone acetyltransferase activity
GO:0004468 ISS lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0004861 ISS cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005671 IDA Ada2/Gcn5/Ada3 transcription activator complex
GO:0006325 TAS chromatin organization
GO:0006338 NAS chromatin remodeling
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006360 TAS transcription from RNA polymerase I promoter
GO:0006361 TAS transcription initiation from RNA polymerase I promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006473 TAS protein acetylation
GO:0007050 TAS cell cycle arrest
GO:0007219 TAS Notch signaling pathway
GO:0008080 IEA N-acetyltransferase activity
GO:0008134 IPI transcription factor binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0010467 TAS gene expression
GO:0010835 IDA regulation of protein ADP-ribosylation
GO:0016032 IEA viral process
GO:0016407 IDA acetyltransferase activity
GO:0016573 IEA histone acetylation
GO:0018076 IDA N-terminal peptidyl-lysine acetylation
GO:0018393 IDA internal peptidyl-lysine acetylation
GO:0018394 IDA peptidyl-lysine acetylation
GO:0019901 ISS protein kinase binding
GO:0031672 IEA A band
GO:0031674 IEA I band
GO:0032403 IDA protein complex binding
GO:0032869 IDA cellular response to insulin stimulus
GO:0035948 IEA positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
GO:0042641 IEA actomyosin
GO:0042826 IPI histone deacetylase binding
GO:0043966 IDA histone H3 acetylation
GO:0043970 IEA histone H3-K9 acetylation
GO:0045736 IEA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062634 kat2b K(lysine) acetyltransferase 2B protein_coding Danio_rerio
ENSMUSG00000000708 Kat2b K(lysine) acetyltransferase 2B protein_coding Mus_musculus

Loading