C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: K(lysine) acetyltransferase 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000708 Kat2b 10090 + 17:53566861-53672720 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000724 Kat2b-001 53566971-53672720 protein_coding
  ENSMUST00000163648 Kat2b-003 53566861-53624491 processed_transcript
  ENSMUST00000164390 Kat2b-002 53584126-53638422 protein_coding
  ENSMUST00000166525 Kat2b-004 53644697-53672071 protein_coding
  ENSMUST00000167092 Kat2b-005 53659238-53663649 retained_intron
  ENSMUST00000171072 Kat2b-006 53659395-53670687 nonsense_mediated_decay
  ENSMUST00000172160 Kat2b-007 53659311-53663674 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000724ENSMUST00000172160
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000724 6.469±1.49 14.366±10.89 14.875±3.30 3.188±1.17 5.064±1.11 6.973±3.93 9.806±0.94 6.059±1.21 6.764±2.19 6.903±1.23 15.211±4.01 4.669±6.20 1.842±1.10 1.496±0.48
ENSMUST00000172160 N/A N/A N/A 12.003±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 13.413±2.84 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004HU CIL_0004HU_0002 CGP 17:53507460-53672720
CIL_0004HV CIL_0004HV_0002 CGP 17:53566861-53689333

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000123 IDA histone acetyltransferase complex
GO:0000776 IDA kinetochore
GO:0003712 IEA transcription cofactor activity
GO:0003713 IDA transcription coactivator activity
GO:0004402 IDA histone acetyltransferase activity
GO:0004468 IDA lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0004861 IDA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005671 IDA Ada2/Gcn5/Ada3 transcription activator complex
GO:0006338 ISS chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006473 TAS protein acetylation
GO:0007049 IEA cell cycle
GO:0008134 IEA transcription factor binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0010835 IEA regulation of protein ADP-ribosylation
GO:0016407 IEA acetyltransferase activity
GO:0016573 IDA histone acetylation
GO:0018076 IEA N-terminal peptidyl-lysine acetylation
GO:0018393 IMP internal peptidyl-lysine acetylation
GO:0018394 IEA peptidyl-lysine acetylation
GO:0019901 IPI protein kinase binding
GO:0031672 IDA A band
GO:0031674 IDA I band
GO:0032403 IEA protein complex binding
GO:0032869 IEA cellular response to insulin stimulus
GO:0035948 IGI positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
GO:0042641 IDA actomyosin
GO:0042826 IEA histone deacetylase binding
GO:0043966 IEA histone H3 acetylation
GO:0043970 IGI histone H3-K9 acetylation
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062634 kat2b K(lysine) acetyltransferase 2B protein_coding Danio_rerio
ENSG00000114166 KAT2B K(lysine) acetyltransferase 2B protein_coding Homo_sapiens

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