C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor suppressor candidate 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114383 TUSC2 9606 - 3:50320027-50328251 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000232496 TUSC2-001 50324907-50328243 protein_coding
  ENST00000417867 TUSC2-005 50326356-50328195 nonsense_mediated_decay
  ENST00000421918 TUSC2-003 50326008-50328251 nonsense_mediated_decay
  ENST00000454201 TUSC2-004 50326008-50328206 nonsense_mediated_decay
  ENST00000462137 TUSC2-007 50320027-50328157 processed_transcript
  ENST00000463304 TUSC2-006 50326090-50328238 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000232496ENST00000462137
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000232496 6.935±0.00 16.114±0.00 2.202±0.00 13.699±4.03 5.930±3.11 5.741±3.23 7.707±6.74 8.783±6.90 10.916±0.00 11.327±0.00 8.432±5.15 10.092±5.07 24.995±3.71 19.604±2.46
ENST00000462137 N/A N/A N/A N/A N/A N/A N/A 3.274±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D8 CIL_0008D8_0001 VISTA 3:50299047-50902727
CIL_0003FI CIL_0003FI_0002 CGP 3:50317790-50328251

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001779 IEA natural killer cell differentiation
GO:0005739 IEA mitochondrion
GO:0006909 IEA phagocytosis
GO:0006954 IEA inflammatory response
GO:0007049 IEA cell cycle
GO:0007267 TAS cell-cell signaling
GO:0008283 TAS cell proliferation
GO:0032618 IEA interleukin-15 production
GO:0032700 IEA negative regulation of interleukin-17 production
GO:0032733 IEA positive regulation of interleukin-10 production
GO:0048469 IEA cell maturation
GO:0050829 IEA defense response to Gram-negative bacterium
GO:0051881 IEA regulation of mitochondrial membrane potential
GO:0052567 IEA response to defense-related host reactive oxygen species production
GO:0070945 IEA neutrophil mediated killing of gram-negative bacterium
GO:0071609 IEA chemokine (C-C motif) ligand 5 production
GO:2000377 IEA regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025340 tusc2b tumor suppressor candidate 2b protein_coding Danio_rerio
ENSDARG00000052875 tusc2a tumor suppressor candidate 2a protein_coding Danio_rerio
ENSMUSG00000010054 Tusc2 tumor suppressor candidate 2 protein_coding Mus_musculus

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