C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor suppressor candidate 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000010054 Tusc2 10090 + 9:107563255-107566108 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000010198 Tusc2-201 107563255-107566108 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000010198
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000010198 28.482±0.66 36.489±1.08 23.277±3.09 34.669±5.05 30.375±9.88 41.474±11.70 17.176±4.12 40.885±3.85 22.092±4.37 30.599±5.25 19.028±3.05 34.924±12.81 23.882±12.57 13.838±5.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D8 CIL_0008D8_0002 VISTA 9:107005935-107609958
CIL_00011B CIL_00011B_0002 CGP 9:107551555-107566108
CIL_000110 CIL_000110_0002 CGP 9:107563255-107572776

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001779 IGI natural killer cell differentiation
GO:0003674 ND molecular_function
GO:0005739 IDA mitochondrion
GO:0006909 IMP phagocytosis
GO:0006954 IMP inflammatory response
GO:0032618 IMP interleukin-15 production
GO:0032700 IMP negative regulation of interleukin-17 production
GO:0032733 IMP positive regulation of interleukin-10 production
GO:0048469 IGI cell maturation
GO:0050829 IMP defense response to Gram-negative bacterium
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0052567 IMP response to defense-related host reactive oxygen species production
GO:0070945 IMP neutrophil mediated killing of gram-negative bacterium
GO:0071609 IMP chemokine (C-C motif) ligand 5 production
GO:2000377 IMP regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025340 tusc2b tumor suppressor candidate 2b protein_coding Danio_rerio
ENSDARG00000052875 tusc2a tumor suppressor candidate 2a protein_coding Danio_rerio
ENSG00000114383 TUSC2 tumor suppressor candidate 2 protein_coding Homo_sapiens

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