C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipid scramblase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114698 PLSCR4 9606 - 3:146192339-146251179 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354952 PLSCR4-001 146192339-146251179 protein_coding
  ENST00000383083 PLSCR4-201 146192339-146251179 protein_coding
  ENST00000433593 PLSCR4-002 146192405-146251079 protein_coding
  ENST00000446574 PLSCR4-004 146194291-146250867 protein_coding
  ENST00000460350 PLSCR4-005 146196632-146251125 protein_coding
  ENST00000460885 PLSCR4-006 146196706-146251105 protein_coding
  ENST00000475019 PLSCR4-011 146196405-146222092 retained_intron
  ENST00000476202 PLSCR4-007 146199813-146251083 protein_coding
  ENST00000481701 PLSCR4-008 146200009-146222433 protein_coding
  ENST00000493382 PLSCR4-003 146194357-146251143 protein_coding
  ENST00000498625 PLSCR4-010 146206587-146222371 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354952ENST00000383083ENST00000433593ENST00000446574ENST00000460350ENST00000493382
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354952 14.455±0.00 2.203±0.00 N/A 3.366±0.65 2.891±0.54 5.656±2.90 1.585±0.00 1.943±0.00 7.168±0.00 3.554±0.00 1.356±0.00 4.848±3.08 2.625±0.64 6.865±0.00
ENST00000383083 N/A N/A 2.061±0.00 N/A 2.997±0.00 N/A N/A 1.091±0.00 N/A N/A N/A N/A N/A N/A
ENST00000433593 22.200±0.00 6.793±0.00 N/A 4.590±0.00 7.755±0.00 11.484±0.00 N/A 4.962±0.00 3.637±0.00 N/A 0.703±0.00 2.735±1.28 3.948±0.00 7.876±0.00
ENST00000446574 N/A N/A N/A 1.334±0.00 N/A N/A N/A N/A N/A N/A N/A 1.352±0.00 N/A 3.460±0.00
ENST00000460350 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.818±0.00 7.429±0.00 7.784±0.00
ENST00000493382 N/A N/A N/A N/A N/A 2.002±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00065H CIL_00065H_0003 CGP 3:146192339-146495991

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 NAS calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0016021 IEA integral component of membrane
GO:0017121 NAS phospholipid scrambling
GO:0017124 IEA SH3 domain binding
GO:0017128 NAS phospholipid scramblase activity
GO:0019899 IPI enzyme binding
GO:0042609 IPI CD4 receptor binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071222 IEA cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045470 FP245465.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000058638 si:ch211-71m22.1 si:ch211-71m22.1 protein_coding Danio_rerio
ENSDARG00000077468 si:ch73-206p6.1 si:ch73-206p6.1 protein_coding Danio_rerio
ENSDARG00000079075 si:ch211-71m22.3 si:ch211-71m22.3 protein_coding Danio_rerio
ENSDARG00000091266 si:ch211-71m22.5 si:ch211-71m22.5 protein_coding Danio_rerio
ENSMUSG00000032377 Plscr4 phospholipid scramblase 4 protein_coding Mus_musculus

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