C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NIMA-related kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114904 NEK4 9606 - 3:52708449-52770949 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233027 NEK4-001 52708449-52770949 protein_coding
  ENST00000383721 NEK4-002 52737498-52770939 protein_coding
  ENST00000461689 NEK4-003 52737586-52770856 protein_coding
  ENST00000487068 NEK4-005 52746150-52752070 nonsense_mediated_decay
  ENST00000493199 NEK4-006 52743228-52746114 retained_intron
  ENST00000496822 NEK4-004 52766316-52770946 nonsense_mediated_decay
  ENST00000535191 NEK4-201 52711777-52770939 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000233027ENST00000383721ENST00000535191
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000233027 3.698±0.00 4.685±0.00 1.908±0.00 4.322±0.63 3.606±0.37 2.882±0.37 1.950±0.65 5.508±1.03 2.498±0.00 2.550±0.66 0.497±0.00 4.600±2.19 22.241±0.00
ENST00000383721 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.073±0.00 N/A N/A N/A
ENST00000535191 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 44.987±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WP CIL_0007WP_0001 VISTA 3:52127966-52731115
CIL_0007GX CIL_0007GX_0002 CGP 3:52694485-52711146
CIL_0007H1 CIL_0007H1_0002 CGP 3:52704955-52770949

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0006468 IEA protein phosphorylation
GO:0007067 IEA mitotic nuclear division
GO:0008152 IEA metabolic process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040152 nek4 NIMA (never in mitosis gene a)-related kinase 4 protein_coding Danio_rerio
ENSMUSG00000021918 Nek4 NIMA (never in mitosis gene a)-related expressed kinase 4 protein_coding Mus_musculus

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