C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutaminyl-peptide cyclotransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115828 QPCT 9606 + 2:37344574-37373322 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000338415 QPCT-001 37344574-37373322 protein_coding
  ENST00000404976 QPCT-004 37344594-37372742 protein_coding
  ENST00000444022 QPCT-006 37368281-37372799 protein_coding
  ENST00000469098 QPCT-005 37367123-37373030 retained_intron
  ENST00000470075 QPCT-002 37344728-37360053 retained_intron
  ENST00000480050 QPCT-003 37358712-37369702 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000338415ENST00000404976ENST00000469098ENST00000470075ENST00000480050
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000338415 3.566±0.00 3.673±0.00 N/A 4.020±3.00 0.859±0.62 11.313±0.00 0.364±0.32 4.620±0.00 0.967±0.00 1.870±1.52 N/A 3.305±2.90 4.999±0.70 2.976±2.67
ENST00000404976 N/A N/A N/A N/A N/A N/A 0.280±0.00 1.452±0.00 N/A 2.170±0.00 1.044±0.00 N/A N/A 0.210±0.00
ENST00000469098 N/A N/A 0.088±0.00 N/A N/A 0.164±0.00 N/A N/A 0.787±0.00 0.654±0.00 N/A N/A N/A N/A
ENST00000470075 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.151±0.00 0.468±0.00 N/A N/A
ENST00000480050 N/A N/A N/A N/A N/A N/A 0.201±0.00 N/A N/A N/A N/A N/A N/A 0.396±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00085G CIL_00085G_0001 VISTA 2:37116727-37718317
CIL_0008VK CIL_0008VK_0001 VISTA 2:37223010-37826535
CIL_0002IN CIL_0002IN_0001 CGP 2:37250502-37373322
CIL_0002IM CIL_0002IM_0001 CGP 2:37344574-37738468

Gene Ontology
GO IDEvidence TypeGO Description
GO:0006464 TAS cellular protein modification process
GO:0008270 IDA zinc ion binding
GO:0016603 IDA glutaminyl-peptide cyclotransferase activity
GO:0017186 IDA peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089717 qpct glutaminyl-peptide cyclotransferase protein_coding Danio_rerio
ENSMUSG00000024084 Qpct glutaminyl-peptide cyclotransferase (glutaminyl cyclase) protein_coding Mus_musculus

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