C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: distal-less homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115844 DLX2 9606 - 2:172099439-172102900 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000234198 DLX2-001 172099439-172102900 protein_coding
  ENST00000466293 DLX2-002 172100557-172102900 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartOvaryPlacentaTestisENST00000234198ENST00000466293
Transcript ID Adipose Brain Breast Colon Heart Ovary Placenta Testis
ENST00000234198 0.019±0.00 0.828±0.00 0.017±0.00 0.009±0.00 N/A 0.065±0.03 N/A 0.141±0.10
ENST00000466293 N/A 0.088±0.00 0.005±0.00 N/A 0.019±0.00 N/A 0.043±0.00 0.102±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RB CIL_0007RB_0001 VISTA 2:171663732-172264836
CIL_0008A7 CIL_0008A7_0001 VISTA 2:171663843-172264792
CIL_0007RB CIL_0007RB_0002 VISTA 2:171664837-172267307
CIL_0008C9 CIL_0008C9_0001 VISTA 2:171771791-172373521
CIL_0009AY CIL_0009AY_0001 VISTA 2:171783051-172384518
CIL_0008AZ CIL_0008AZ_0001 VISTA 2:171791151-172392324
CIL_0008B0 CIL_0008B0_0001 VISTA 2:171792917-172394318
CIL_00062L CIL_00062L_0002 CGP 2:172084740-172102900
CIL_0003IK CIL_0003IK_0002 CGP 2:172099439-172506282

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003727 IEA single-stranded RNA binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007420 TAS brain development
GO:0009954 IEA proximal/distal pattern formation
GO:0021544 IEA subpallium development
GO:0021766 IEA hippocampus development
GO:0021772 IEA olfactory bulb development
GO:0021879 IEA forebrain neuron differentiation
GO:0021882 IEA regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
GO:0021892 IEA cerebral cortex GABAergic interneuron differentiation
GO:0021893 IEA cerebral cortex GABAergic interneuron fate commitment
GO:0030154 IEA cell differentiation
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043565 IEA sequence-specific DNA binding
GO:0045746 IEA negative regulation of Notch signaling pathway
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048701 IEA embryonic cranial skeleton morphogenesis
GO:0048706 IEA embryonic skeletal system development
GO:0048715 IEA negative regulation of oligodendrocyte differentiation
GO:0048755 IEA branching morphogenesis of a nerve
GO:0051216 IEA cartilage development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079964 dlx2a distal-less homeobox gene 2a protein_coding Danio_rerio
ENSMUSG00000023391 Dlx2 distal-less homeobox 2 protein_coding Mus_musculus

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