C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: distal-less homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023391 Dlx2 10090 - 2:71543408-71546754 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024159 Dlx2-001 71543408-71546754 protein_coding
  ENSMUST00000134249 Dlx2-002 71544866-71545950 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000024159ENSMUST00000134249
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000024159 0.158±0.04 N/A 8.431±5.58 0.026±0.01 0.083±0.04 0.011±0.00 0.009±0.00 0.027±0.02 0.014±0.00 0.016±0.00 0.060±0.03 0.031±0.02
ENSMUST00000134249 N/A 0.020±0.00 0.678±0.00 N/A N/A N/A N/A N/A N/A N/A 0.091±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RB CIL_0007RB_0003 VISTA 2:71118479-71722071
CIL_0008A7 CIL_0008A7_0002 VISTA 2:71118555-71719483
CIL_0008C9 CIL_0008C9_0002 VISTA 2:71216484-71818219
CIL_0009AY CIL_0009AY_0002 VISTA 2:71227336-71828847
CIL_0008AZ CIL_0008AZ_0002 VISTA 2:71235378-71836557
CIL_0008B0 CIL_0008B0_0002 VISTA 2:71237156-71838581
CIL_00062L CIL_00062L_0003 CGP 2:71528113-71546754
CIL_0003IK CIL_0003IK_0003 CGP 2:71543408-71858416

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003727 IPI single-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0009954 IGI proximal/distal pattern formation
GO:0021544 IGI subpallium development
GO:0021766 IGI hippocampus development
GO:0021772 IMP olfactory bulb development
GO:0021879 IGI forebrain neuron differentiation
GO:0021882 IGI regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
GO:0021892 IGI cerebral cortex GABAergic interneuron differentiation
GO:0021893 IGI cerebral cortex GABAergic interneuron fate commitment
GO:0030154 IMP cell differentiation
GO:0042475 IGI odontogenesis of dentin-containing tooth
GO:0043565 IEA sequence-specific DNA binding
GO:0045746 IGI negative regulation of Notch signaling pathway
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0048706 IGI embryonic skeletal system development
GO:0048715 IGI negative regulation of oligodendrocyte differentiation
GO:0048755 IMP branching morphogenesis of a nerve
GO:0051216 IMP cartilage development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079964 dlx2a distal-less homeobox gene 2a protein_coding Danio_rerio
ENSG00000115844 DLX2 distal-less homeobox 2 protein_coding Homo_sapiens

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