C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116641 DOCK7 9606 - 1:62454728-62688368 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000251157 DOCK7-201 62454728-62688368 protein_coding
  ENST00000340370 DOCK7-004 62454898-62688282 protein_coding
  ENST00000404627 DOCK7-001 62584106-62688282 protein_coding
  ENST00000454575 DOCK7-002 62454898-62555934 protein_coding
  ENST00000464312 DOCK7-006 62625098-62633546 processed_transcript
  ENST00000467758 DOCK7-007 62475212-62476189 processed_transcript
  ENST00000479983 DOCK7-003 62492306-62495298 processed_transcript
  ENST00000489185 DOCK7-005 62474010-62479004 processed_transcript
  ENST00000614472 DOCK7-202 62543726-62653789 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000251157ENST00000340370ENST00000404627ENST00000454575ENST00000614472
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000251157 N/A 0.369±0.00 0.696±0.00 1.188±0.00 1.309±0.00 N/A N/A 0.208±0.00 0.486±0.23 N/A 1.706±0.00 N/A N/A
ENST00000340370 0.737±0.00 0.443±0.00 1.112±0.00 1.369±0.08 N/A 0.292±0.00 N/A 1.176±0.75 N/A N/A 0.940±0.00 1.381±0.00 2.413±0.00
ENST00000404627 N/A N/A 2.500±0.71 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000454575 1.590±0.00 1.524±0.00 2.496±0.76 3.155±1.20 2.438±0.44 0.833±0.50 2.325±0.00 1.524±0.67 1.179±0.13 1.069±0.71 3.347±1.02 2.050±0.91 5.975±0.71
ENST00000614472 N/A N/A N/A 2.028±0.00 N/A 0.638±0.00 N/A N/A N/A 0.579±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002G2 CIL_0002G2_0001 CGP 1:62436297-62688368
CIL_000051 CIL_000051_0002 CGP 1:62454728-62688368

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IMP microtubule cytoskeleton organization
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005925 IDA focal adhesion
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007409 IMP axonogenesis
GO:0008180 IDA COP9 signalosome
GO:0022027 ISS interkinetic nuclear migration
GO:0030424 TAS axon
GO:0030426 TAS growth cone
GO:0031175 IMP neuron projection development
GO:0032863 IDA activation of Rac GTPase activity
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0043005 TAS neuron projection
GO:0043473 IEA pigmentation
GO:0045178 TAS basal part of cell
GO:0045200 IMP establishment of neuroblast polarity
GO:0048365 IDA Rac GTPase binding
GO:0050767 ISS regulation of neurogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078675 dock7 dedicator of cytokinesis 7 protein_coding Danio_rerio
ENSMUSG00000028556 Dock7 dedicator of cytokinesis 7 protein_coding Mus_musculus

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