C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dedicator of cytokinesis 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000251157 DOCK7-201 ENSG00000116641 9606 - 1:62454728-62688368 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonLiverLungOvaryENST00000251157
Transcript ID Adrenal Brain Breast Colon Liver Lung Ovary
ENST00000251157 0.369±0.00 0.696±0.00 1.188±0.00 1.309±0.00 0.208±0.00 0.486±0.23 1.706±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002G2 CIL_0002G2_0001 CGP 1:62436297-62688368
CIL_000051 CIL_000051_0002 CGP 1:62454728-62688368

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000226 IMP microtubule cytoskeleton organization
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005925 IDA focal adhesion
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007409 IMP axonogenesis
GO:0008180 IDA COP9 signalosome
GO:0022027 ISS interkinetic nuclear migration
GO:0030424 TAS axon
GO:0030426 TAS growth cone
GO:0031175 IMP neuron projection development
GO:0032863 IDA activation of Rac GTPase activity
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0043005 TAS neuron projection
GO:0043473 IEA pigmentation
GO:0045178 TAS basal part of cell
GO:0045200 IMP establishment of neuroblast polarity
GO:0048365 IDA Rac GTPase binding
GO:0050767 ISS regulation of neurogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000030286 Dock7-001 protein_coding Mus_musculus 0 8552
ENSMUST00000075836 Dock7-201 protein_coding Mus_musculus 0 4789
ENSMUST00000124466 Dock7-002 processed_transcript Mus_musculus 0 4638
ENSMUST00000127417 Dock7-007 protein_coding Mus_musculus 0 3029
ENSMUST00000127946 Dock7-005 protein_coding Mus_musculus 0 911
ENSMUST00000124040 Dock7-011 processed_transcript Mus_musculus 0 869
ENSMUST00000150254 Dock7-004 protein_coding Mus_musculus 0 830
ENSMUST00000139152 Dock7-008 processed_transcript Mus_musculus 0 739
ENSMUST00000153362 Dock7-006 processed_transcript Mus_musculus 0 527

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