C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MAD2 mitotic arrest deficient-like 2 (yeast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116670 MAD2L2 9606 - 1:11674480-11691650 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000235310 MAD2L2-001 11674480-11691650 protein_coding
  ENST00000376655 MAD2L2-005 11676872-11691593 retained_intron
  ENST00000376664 MAD2L2-008 11675700-11681111 retained_intron
  ENST00000376667 MAD2L2-003 11674748-11691609 protein_coding
  ENST00000376669 MAD2L2-002 11674678-11681118 protein_coding
  ENST00000376672 MAD2L2-004 11674525-11691477 protein_coding
  ENST00000376692 MAD2L2-201 11674481-11681214 protein_coding
  ENST00000445656 MAD2L2-007 11675656-11681111 protein_coding
  ENST00000456915 MAD2L2-006 11675657-11681131 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000235310ENST00000376655ENST00000376664ENST00000376667ENST00000376669ENST00000376672ENST00000376692
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000235310 N/A N/A N/A N/A N/A N/A 0.170±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000376655 N/A N/A N/A N/A N/A 0.694±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000376664 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.626±0.00 N/A N/A N/A N/A
ENST00000376667 N/A N/A N/A N/A N/A 0.813±0.00 N/A N/A 0.292±0.00 N/A N/A 2.596±0.00 0.888±0.00 N/A
ENST00000376669 N/A N/A 0.116±0.00 4.349±0.00 N/A N/A 0.561±0.00 N/A N/A N/A 3.943±0.00 5.783±0.00 0.885±0.00 N/A
ENST00000376672 N/A N/A 0.182±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000376692 27.808±0.00 31.633±0.00 N/A 8.612±6.27 10.356±7.81 23.374±0.00 4.998±4.18 9.899±7.84 12.261±12.04 21.479±20.62 16.799±12.51 18.868±13.25 11.861±5.40 34.857±16.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0001 VISTA 1:11580820-12184055

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001558 IGI regulation of cell growth
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005680 IDA anaphase-promoting complex
GO:0005737 IEA cytoplasm
GO:0005819 IDA spindle
GO:0006281 TAS DNA repair
GO:0006302 IGI double-strand break repair
GO:0006351 IEA transcription, DNA-templated
GO:0007015 IMP actin filament organization
GO:0007067 IEA mitotic nuclear division
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0008432 IDA JUN kinase binding
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0010944 IMP negative regulation of transcription by competitive promoter binding
GO:0016035 IDA zeta DNA polymerase complex
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0042177 IDA negative regulation of protein catabolic process
GO:0042772 IDA DNA damage response, signal transduction resulting in transcription
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0060564 IDA negative regulation of mitotic anaphase-promoting complex activity
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:2000048 IMP negative regulation of cell-cell adhesion mediated by cadherin
GO:2000678 IMP negative regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007096 MAD2L2 (1 of 2) MAD2 mitotic arrest deficient-like 2 (yeast) protein_coding Danio_rerio
ENSDARG00000042456 MAD2L2 (2 of 2) MAD2 mitotic arrest deficient-like 2 (yeast) protein_coding Danio_rerio
ENSMUSG00000029003 Mad2l2 MAD2 mitotic arrest deficient-like 2 protein_coding Mus_musculus

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