C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MAD2 mitotic arrest deficient-like 2 (yeast)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000376692 MAD2L2-201 ENSG00000116670 9606 - 1:11674481-11681214 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376692
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376692 27.808±0.00 31.633±0.00 8.612±6.27 10.356±7.81 23.374±0.00 4.998±4.18 9.899±7.84 12.261±12.04 21.479±20.62 16.799±12.51 18.868±13.25 11.861±5.40 34.857±16.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0001 VISTA 1:11580820-12184055

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001558 IGI regulation of cell growth
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005680 IDA anaphase-promoting complex
GO:0005737 IEA cytoplasm
GO:0005819 IDA spindle
GO:0006281 TAS DNA repair
GO:0006302 IGI double-strand break repair
GO:0006351 IEA transcription, DNA-templated
GO:0007015 IMP actin filament organization
GO:0007067 IEA mitotic nuclear division
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0008432 IDA JUN kinase binding
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0010944 IMP negative regulation of transcription by competitive promoter binding
GO:0016035 IDA zeta DNA polymerase complex
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0042177 IDA negative regulation of protein catabolic process
GO:0042772 IDA DNA damage response, signal transduction resulting in transcription
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0060564 IDA negative regulation of mitotic anaphase-promoting complex activity
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:2000048 IMP negative regulation of cell-cell adhesion mediated by cadherin
GO:2000678 IMP negative regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000030860 Mad2l2-003 protein_coding Mus_musculus 0 811
ENSMUST00000084129 Mad2l2-001 protein_coding Mus_musculus 0 811
ENSMUST00000105707 Mad2l2-005 protein_coding Mus_musculus 0 691
ENSMUST00000132698 Mad2l2-004 protein_coding Mus_musculus 0 662
ENSMUST00000148742 Mad2l2-007 retained_intron Mus_musculus 0 318
ENSMUST00000105708 Mad2l2-008 retained_intron Mus_musculus 3.99931e-42 176
ENSMUST00000140049 Mad2l2-006 protein_coding Mus_musculus 1e-31 141

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