C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth arrest and DNA-damage-inducible, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116717 GADD45A 9606 + 1:67685061-67688338 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370985 GADD45A-003 67685201-67687887 protein_coding
  ENST00000370986 GADD45A-001 67685061-67688338 protein_coding
  ENST00000460575 GADD45A-002 67685229-67686588 processed_transcript
  ENST00000484245 GADD45A-004 67685676-67686586 processed_transcript
  ENST00000617962 GADD45A-201 67685177-67688338 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370985ENST00000370986ENST00000460575ENST00000484245ENST00000617962
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370985 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.921±0.00 N/A N/A N/A N/A
ENST00000370986 30.084±0.00 N/A 2.341±0.00 20.609±0.00 1.553±0.64 13.806±0.00 3.360±0.00 9.222±0.00 4.802±0.80 19.273±19.04 16.794±0.00 9.512±6.26 11.210±3.03 8.007±0.00
ENST00000460575 N/A N/A N/A N/A 7.130±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000484245 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.828±0.00 N/A 1.513±0.00 N/A N/A
ENST00000617962 22.785±0.00 6.988±0.00 4.854±0.00 7.887±6.04 4.921±0.00 5.945±2.73 1.661±1.22 25.278±0.00 N/A N/A 17.613±0.00 9.516±9.20 14.800±0.00 4.478±1.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 TAS regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000185 IDA activation of MAPKKK activity
GO:0001047 IEA core promoter binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006281 TAS DNA repair
GO:0006469 IEA negative regulation of protein kinase activity
GO:0006915 TAS apoptotic process
GO:0007050 IEA cell cycle arrest
GO:0007098 IEA centrosome cycle
GO:0042770 IMP signal transduction in response to DNA damage
GO:0043065 IDA positive regulation of apoptotic process
GO:0046330 IDA positive regulation of JNK cascade
GO:0051726 IEA regulation of cell cycle
GO:0071260 IEP cellular response to mechanical stimulus
GO:0071479 IMP cellular response to ionizing radiation
GO:1900745 IDA positive regulation of p38MAPK cascade
GO:2000379 IMP positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000036390 Gadd45a growth arrest and DNA-damage-inducible 45 alpha protein_coding Mus_musculus

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