C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth arrest and DNA-damage-inducible 45 alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036390 Gadd45a 10090 - 6:67035096-67037457 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043098 Gadd45a-001 67035096-67037406 protein_coding
  ENSMUST00000126194 Gadd45a-003 67036371-67037377 retained_intron
  ENSMUST00000128617 Gadd45a-005 67035579-67037186 retained_intron
  ENSMUST00000151958 Gadd45a-004 67035459-67037201 retained_intron
  ENSMUST00000155041 Gadd45a-002 67036897-67037457 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043098ENSMUST00000126194ENSMUST00000151958ENSMUST00000155041
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043098 7.399±0.92 7.520±3.25 25.820±6.13 3.048±0.73 3.913±1.67 9.983±0.67 4.587±1.19 10.017±2.32 24.521±26.45 4.412±0.42 11.321±1.50 27.350±17.70 11.649±1.78 0.777±0.49
ENSMUST00000126194 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.572±0.24
ENSMUST00000151958 N/A N/A N/A 2.352±0.00 3.766±0.00 N/A N/A N/A N/A N/A N/A N/A 8.756±0.00 0.247±0.00
ENSMUST00000155041 10.333±2.40 7.780±0.00 N/A N/A 6.196±0.45 13.392±2.44 N/A 8.658±0.04 N/A 4.779±1.09 N/A 25.342±4.50 N/A 0.900±0.17

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000185 IEA activation of MAPKKK activity
GO:0001047 IDA core promoter binding
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005737 IEA cytoplasm
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007050 IEA cell cycle arrest
GO:0007098 IGI centrosome cycle
GO:0042770 IEA signal transduction in response to DNA damage
GO:0043065 IEA positive regulation of apoptotic process
GO:0046330 IEA positive regulation of JNK cascade
GO:0051726 IDA regulation of cell cycle
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071479 IEA cellular response to ionizing radiation
GO:1900745 IEA positive regulation of p38MAPK cascade
GO:2000379 IEA positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000116717 GADD45A growth arrest and DNA-damage-inducible, alpha protein_coding Homo_sapiens

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