C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth arrest and DNA-damage-inducible, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000370985 GADD45A-003 ENSG00000116717 9606 + 1:67685201-67687887 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungENST00000370985
Transcript ID Lung
ENST00000370985 0.921±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000079 TAS regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000185 IDA activation of MAPKKK activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006281 TAS DNA repair
GO:0006915 TAS apoptotic process
GO:0007050 IEA cell cycle arrest
GO:0042770 IMP signal transduction in response to DNA damage
GO:0043065 IDA positive regulation of apoptotic process
GO:0046330 IDA positive regulation of JNK cascade
GO:0071260 IEP cellular response to mechanical stimulus
GO:0071479 IMP cellular response to ionizing radiation
GO:1900745 IDA positive regulation of p38MAPK cascade
GO:2000379 IMP positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000151958 Gadd45a-004 retained_intron Mus_musculus 0 638
ENSMUST00000043098 Gadd45a-001 protein_coding Mus_musculus 0 638
ENSMUST00000128617 Gadd45a-005 retained_intron Mus_musculus 0 592
ENSMUST00000126194 Gadd45a-003 retained_intron Mus_musculus 0 289
ENSDART00000063996 gadd45aa-001 protein_coding Danio_rerio 2e-29 134
ENSMUST00000155041 Gadd45a-002 retained_intron Mus_musculus 4e-16 90

Loading