C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117009 KMO 9606 + 1:241532134-241595642 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366555 KMO-004 241568635-241593459 protein_coding
  ENST00000366557 KMO-003 241532405-241595642 protein_coding
  ENST00000366558 KMO-002 241532134-241592288 protein_coding
  ENST00000366559 KMO-001 241532134-241595642 protein_coding
  ENST00000431245 KMO-009 241562053-241586736 processed_transcript
  ENST00000477907 KMO-008 241532401-241566575 processed_transcript
  ENST00000480967 KMO-006 241532369-241562283 processed_transcript
  ENST00000481087 KMO-010 241549662-241555801 processed_transcript
  ENST00000484229 KMO-007 241532379-241550087 processed_transcript
  ENST00000484628 KMO-005 241532338-241562264 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderColonKidneyLiverENST00000366557ENST00000366558ENST00000366559ENST00000484229
Transcript ID Adrenal Bladder Colon Kidney Liver
ENST00000366557 N/A 1.962±0.00 0.262±0.00 6.375±0.00 0.123±0.00
ENST00000366558 N/A N/A N/A 10.856±0.00 2.054±0.00
ENST00000366559 0.312±0.00 N/A N/A N/A N/A
ENST00000484229 N/A N/A N/A N/A 0.730±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000HM CIL_0000HM_0001 CGP 1:241497603-241595642
CIL_0000I7 CIL_0000I7_0001 CGP 1:241532134-241677376

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004502 IDA kynurenine 3-monooxygenase activity
GO:0005739 IEA mitochondrion
GO:0005741 ISS mitochondrial outer membrane
GO:0005743 IEA mitochondrial inner membrane
GO:0005829 TAS cytosol
GO:0006569 TAS tryptophan catabolic process
GO:0009651 IDA response to salt stress
GO:0016021 IEA integral component of membrane
GO:0016174 IDA NAD(P)H oxidase activity
GO:0019441 IEA tryptophan catabolic process to kynurenine
GO:0019674 IEA NAD metabolic process
GO:0019805 IEA quinolinate biosynthetic process
GO:0034354 IEA 'de novo' NAD biosynthetic process from tryptophan
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0043420 IEA anthranilate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0050660 IDA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0070189 IDA kynurenine metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009160 kmo kynurenine 3-monooxygenase protein_coding Danio_rerio
ENSDARG00000088056 KMO (2 of 2) kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) protein_coding Danio_rerio
ENSMUSG00000039783 Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) protein_coding Mus_musculus

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