C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117505 DR1 9606 + 1:93345888-93369498 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370267 DR1-002 93345935-93361168 protein_coding
  ENST00000370272 DR1-001 93345888-93369498 protein_coding
  ENST00000481583 DR1-003 93354975-93360935 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370267ENST00000370272
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370267 14.115±0.00 N/A N/A 8.165±0.00 N/A N/A 3.442±0.00 N/A 11.755±0.00 14.143±0.00 9.185±0.00 12.298±0.00 12.583±0.28 48.088±12.79
ENST00000370272 3.437±0.00 4.467±0.00 2.706±0.00 3.228±0.10 3.642±0.04 3.500±0.16 0.982±0.00 3.379±0.00 3.461±0.00 4.649±0.00 1.819±1.09 2.956±0.24 2.740±0.59 5.307±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ZW CIL_0005ZW_0001 CGP 1:93179919-93369498

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0003677 TAS DNA binding
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005671 IDA Ada2/Gcn5/Ada3 transcription activator complex
GO:0006325 TAS chromatin organization
GO:0006351 IEA transcription, DNA-templated
GO:0008134 TAS transcription factor binding
GO:0017025 IDA TBP-class protein binding
GO:0043565 IEA sequence-specific DNA binding
GO:0043966 IDA histone H3 acetylation
GO:0046982 IEA protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059752 dr1 down-regulator of transcription 1 protein_coding Danio_rerio
ENSMUSG00000029265 Dr1 down-regulator of transcription 1 protein_coding Mus_musculus

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