C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, nicotinic, beta 4 (neuronal)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117971 CHRNB4 9606 - 15:78624119-78727754 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261751 CHRNB4-001 78624119-78641245 protein_coding
  ENST00000412074 CHRNB4-003 78624408-78641245 protein_coding
  ENST00000558216 CHRNB4-005 78692578-78727754 processed_transcript
  ENST00000559849 CHRNB4-002 78629353-78660532 nonsense_mediated_decay
  ENST00000560511 CHRNB4-004 78631062-78720286 processed_transcript
  ENST00000560868 CHRNB4-006 78686918-78708052 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000261751ENST00000412074ENST00000558216ENST00000559849ENST00000560868
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000261751 N/A 1.523±0.00 N/A N/A 0.454±0.05 N/A N/A N/A N/A N/A 0.112±0.04 2.498±1.86
ENST00000412074 0.112±0.00 N/A N/A N/A N/A 0.016±0.00 N/A N/A 0.113±0.00 0.029±0.00 N/A N/A
ENST00000558216 0.092±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000559849 0.032±0.00 N/A 0.081±0.00 0.049±0.00 N/A 0.030±0.00 0.082±0.00 0.007±0.00 0.060±0.00 0.007±0.00 0.015±0.00 N/A
ENST00000560868 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.241±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001KZ CIL_0001KZ_0001 CGP 15:78593052-78727754

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001508 IEA action potential
GO:0004889 TAS acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 TAS plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0005892 TAS acetylcholine-gated channel complex
GO:0006810 IEA transport
GO:0006811 TAS:IEA ion transport
GO:0006812 TAS cation transport
GO:0006939 IEA smooth muscle contraction
GO:0006940 IEA regulation of smooth muscle contraction
GO:0007165 IDA signal transduction
GO:0007268 TAS synaptic transmission
GO:0007271 TAS synaptic transmission, cholinergic
GO:0007626 IEA locomotory behavior
GO:0015276 TAS ligand-gated ion channel activity
GO:0015464 IDA acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0034220 TAS ion transmembrane transport
GO:0035094 IEA response to nicotine
GO:0035095 IEA behavioral response to nicotine
GO:0042391 IEA regulation of membrane potential
GO:0045211 IEA postsynaptic membrane
GO:0046928 NAS regulation of neurotransmitter secretion
GO:0060084 IMP synaptic transmission involved in micturition
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019983 CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) protein_coding Danio_rerio
ENSMUSG00000035200 Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 protein_coding Mus_musculus

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