C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box and leucine-rich repeat protein 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118564 FBXL5 9606 - 4:15604539-15681679 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341285 FBXL5-001 15604539-15655412 protein_coding
  ENST00000412094 FBXL5-002 15605006-15655382 protein_coding
  ENST00000503196 FBXL5-010 15638539-15659867 protein_coding
  ENST00000504837 FBXL5-006 15636373-15655295 retained_intron
  ENST00000507700 FBXL5-003 15612013-15655341 retained_intron
  ENST00000507899 FBXL5-008 15640841-15681554 protein_coding
  ENST00000509314 FBXL5-011 15638549-15659864 protein_coding
  ENST00000510802 FBXL5-013 15638690-15681567 protein_coding
  ENST00000511441 FBXL5-004 15605006-15655341 nonsense_mediated_decay
  ENST00000512066 FBXL5-007 15636590-15644678 protein_coding
  ENST00000513163 FBXL5-005 15605006-15644649 protein_coding
  ENST00000514541 FBXL5-009 15659731-15681679 processed_transcript
  ENST00000515679 FBXL5-012 15640849-15681619 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000341285ENST00000412094ENST00000507700ENST00000513163
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000341285 6.808±0.00 6.891±0.00 6.425±0.00 9.827±1.55 10.293±4.46 4.216±0.00 5.387±1.59 7.347±0.00 5.476±3.32 5.992±0.90 4.307±0.00 16.001±4.50 6.887±0.75 12.034±0.00
ENST00000412094 16.819±0.00 6.959±0.00 12.022±0.00 12.600±3.10 19.664±12.50 13.759±1.13 12.665±4.19 15.541±6.56 7.943±2.50 11.168±1.94 5.921±0.97 13.382±4.26 13.489±8.97 42.892±18.31
ENST00000507700 N/A N/A N/A N/A 6.391±0.00 N/A N/A N/A 6.210±0.00 8.191±0.00 N/A 5.688±0.00 N/A N/A
ENST00000513163 18.285±0.00 13.887±0.00 N/A 14.095±0.00 20.528±0.00 7.331±0.00 10.179±0.00 23.263±0.00 8.648±0.00 15.773±0.00 15.333±0.00 22.063±0.00 10.440±0.57 21.560±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00026J CIL_00026J_0001 CGP 4:15469865-15681679

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 NAS ubiquitin ligase complex
GO:0004842 NAS ubiquitin-protein transferase activity
GO:0005506 IDA iron ion binding
GO:0005515 IPI:IEA protein binding
GO:0016567 IEA protein ubiquitination
GO:0019005 IDA SCF ubiquitin ligase complex
GO:0031146 IDA SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0048471 IDA perinuclear region of cytoplasm
GO:0055072 IMP iron ion homeostasis
GO:1903364 IEA positive regulation of cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043046 fbxl5 F-box and leucine-rich repeat protein 5 protein_coding Danio_rerio
ENSMUSG00000039753 Fbxl5 F-box and leucine-rich repeat protein 5 protein_coding Mus_musculus

Loading