C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: secreted phosphoprotein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118785 SPP1 9606 + 4:87975650-87983426 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237623 SPP1-002 87975667-87983426 protein_coding
  ENST00000360804 SPP1-003 87975714-87983127 protein_coding
  ENST00000395080 SPP1-001 87975688-87983297 protein_coding
  ENST00000504310 SPP1-007 87975714-87978024 retained_intron
  ENST00000505146 SPP1-011 87976880-87980188 retained_intron
  ENST00000508002 SPP1-006 87975717-87980688 retained_intron
  ENST00000508233 SPP1-010 87975714-87982798 protein_coding
  ENST00000509334 SPP1-009 87975714-87981761 processed_transcript
  ENST00000509659 SPP1-004 87975715-87983326 processed_transcript
  ENST00000513981 SPP1-008 87975714-87981678 processed_transcript
  ENST00000614857 SPP1-201 87975650-87983410 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000237623ENST00000360804ENST00000395080ENST00000508002ENST00000508233ENST00000614857
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000237623 0.821±0.00 0.556±0.00 22.559±0.00 10.506±0.00 4.072±0.00 6.664±0.00 1.101±0.00 492.265±0.00 1.546±0.00 0.281±0.00 N/A 6.958±5.32 79.558±17.03 0.795±0.00
ENST00000360804 N/A N/A N/A N/A N/A N/A 0.053±0.00 826.750±0.00 2.862±0.00 4.559±3.58 0.344±0.00 1.427±0.00 N/A 0.413±0.00
ENST00000395080 3.217±0.00 3.448±0.00 85.926±0.00 103.283±73.58 13.888±0.79 13.625±12.80 3.922±0.00 1114.666±1114.53 3.612±3.29 3.082±2.38 0.318±0.00 15.506±12.50 492.247±290.35 3.079±0.00
ENST00000508002 N/A N/A N/A N/A N/A N/A N/A 0.774±0.00 N/A N/A N/A N/A N/A N/A
ENST00000508233 2.478±0.00 2.541±0.00 N/A 243.768±0.00 14.795±0.00 24.866±0.00 3.624±0.00 1509.420±0.00 5.377±0.00 15.496±0.00 N/A 8.009±0.00 654.841±0.00 0.472±0.00
ENST00000614857 N/A N/A N/A 69.416±0.00 3.270±0.00 N/A N/A N/A N/A 2.380±0.00 N/A 1.971±0.00 N/A 0.612±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000BJ CIL_0000BJ_0001 CGP 4:87821411-87983426
CIL_0000BK CIL_0000BK_0001 CGP 4:87975650-88077777

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001649 IEA osteoblast differentiation
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0006954 IEA inflammatory response
GO:0007155 IEA cell adhesion
GO:0007566 TAS embryo implantation
GO:0010033 IEA response to organic substance
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0022617 TAS extracellular matrix disassembly
GO:0030154 IEA cell differentiation
GO:0030198 TAS extracellular matrix organization
GO:0030593 IEA neutrophil chemotaxis
GO:0031214 IEA biomineral tissue development
GO:0031988 IEA membrane-bounded vesicle
GO:0033280 IDA response to vitamin D
GO:0042995 IEA cell projection
GO:0045177 IEA apical part of cell
GO:0045780 IEA positive regulation of bone resorption
GO:0046697 TAS decidualization
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048545 IEA response to steroid hormone
GO:0048685 IEA negative regulation of collateral sprouting of intact axon in response to injury
GO:0050840 IEA extracellular matrix binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000029304 Spp1 secreted phosphoprotein 1 protein_coding Mus_musculus

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