C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: placental growth factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119630 PGF 9606 - 14:74941834-74955784 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000238607 PGF-002 74941858-74955577 protein_coding
  ENST00000405431 PGF-008 74942706-74955242 protein_coding
  ENST00000553716 PGF-003 74941841-74955626 protein_coding
  ENST00000555234 PGF-004 74948400-74955597 retained_intron
  ENST00000555253 PGF-006 74944564-74948215 retained_intron
  ENST00000555567 PGF-001 74941834-74955784 protein_coding
  ENST00000556939 PGF-005 74948129-74955597 retained_intron
  ENST00000557748 PGF-007 74942494-74954234 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000238607ENST00000405431ENST00000553716ENST00000555253ENST00000555567ENST00000557748
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000238607 8.146±0.00 11.662±0.00 N/A N/A 2.349±0.00 3.322±0.00 1.423±0.00 0.789±0.00 0.595±0.14 N/A 0.374±0.00 2.316±0.41 51.574±30.07 3.617±0.00
ENST00000405431 N/A N/A N/A N/A N/A N/A 0.421±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000553716 6.472±0.00 9.963±0.00 N/A 1.456±0.00 1.595±0.00 0.448±0.41 1.240±1.09 2.099±0.00 2.439±0.00 1.358±0.00 N/A 2.325±1.10 62.587±43.34 3.453±0.00
ENST00000555253 N/A N/A 0.027±0.00 0.146±0.12 N/A N/A 0.088±0.00 0.014±0.00 N/A 0.231±0.00 N/A 0.207±0.00 2.141±0.00 0.076±0.00
ENST00000555567 N/A N/A N/A 0.165±0.00 1.751±0.00 0.610±0.00 0.538±0.00 N/A N/A 3.004±0.00 1.171±0.00 0.823±0.28 N/A 1.377±0.25
ENST00000557748 N/A N/A 0.178±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003TN CIL_0003TN_0001 CGP 14:74903954-74955784
CIL_00084S CIL_00084S_0001 VISTA 14:74936670-75538350
CIL_0003G0 CIL_0003G0_0001 CGP 14:74941834-75012366

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001666 IEA response to hypoxia
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0002040 IEA sprouting angiogenesis
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0007565 IEA female pregnancy
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0016020 IEA membrane
GO:0030154 IEA cell differentiation
GO:0031100 IEA organ regeneration
GO:0032870 IEA cellular response to hormone stimulus
GO:0042493 IEA response to drug
GO:0042803 IEA protein homodimerization activity
GO:0045766 IEA positive regulation of angiogenesis
GO:0046982 IEA protein heterodimerization activity
GO:0048010 TAS vascular endothelial growth factor receptor signaling pathway
GO:0051781 IEA positive regulation of cell division
GO:0060688 IEA regulation of morphogenesis of a branching structure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076767 PGF (1 of 2) placental growth factor protein_coding Danio_rerio
ENSDARG00000091096 CABZ01077555.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000004791 Pgf placental growth factor protein_coding Mus_musculus

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