C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor 68
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119714 GPR68 9606 - 14:91232532-91253925 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000529102 GPR68-002 91234037-91244508 protein_coding
  ENST00000529300 GPR68-003 91235118-91253880 processed_transcript
  ENST00000531499 GPR68-001 91232532-91253925 protein_coding
  ENST00000535815 GPR68-201 91232533-91244508 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000529102ENST00000529300ENST00000531499ENST00000535815
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000529102 N/A N/A 1.019±0.00 0.127±0.00 1.110±0.00 0.446±0.13 0.347±0.00 N/A 0.974±0.93 1.295±0.00 0.341±0.29 0.384±0.00 1.009±0.00 0.865±0.00
ENST00000529300 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.296±0.00 N/A N/A N/A
ENST00000531499 0.514±0.00 7.671±0.00 N/A 0.398±0.00 0.758±0.00 0.339±0.00 0.162±0.00 0.460±0.39 0.550±0.00 9.076±0.00 0.053±0.00 1.000±0.27 2.116±0.93 N/A
ENST00000535815 N/A N/A 0.121±0.00 0.215±0.00 0.179±0.00 N/A N/A N/A N/A N/A N/A N/A 0.516±0.19 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038W CIL_00038W_0001 CGP 14:91060333-91253925
CIL_0001UN CIL_0001UN_0001 CGP 14:91232532-91417844

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006954 TAS inflammatory response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0032024 IEA positive regulation of insulin secretion
GO:0035774 IEA positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0045656 IEA negative regulation of monocyte differentiation
GO:0071467 IEA cellular response to pH
GO:2001206 IEA positive regulation of osteoclast development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053711 GPR68 G protein-coupled receptor 68 protein_coding Danio_rerio
ENSMUSG00000047415 Gpr68 G protein-coupled receptor 68 protein_coding Mus_musculus

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