C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor 68
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000047415 Gpr68 10090 - 12:100876682-100908198 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053668 Gpr68-201 100876685-100899524 protein_coding
  ENSMUST00000110065 Gpr68-002 100876685-100908181 protein_coding
  ENSMUST00000110066 Gpr68-001 100876682-100908198 protein_coding
  ENSMUST00000124459 Gpr68-003 100887684-100908198 processed_transcript
  ENSMUST00000128306 Gpr68-004 100887872-100899524 processed_transcript
  ENSMUST00000135684 Gpr68-005 100879314-100899498 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053668ENSMUST00000110065ENSMUST00000110066ENSMUST00000135684
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053668 0.294±0.05 0.275±0.15 0.284±0.12 0.725±0.35 2.400±0.97 0.719±0.32 N/A 0.292±0.16 0.020±0.01 0.782±0.18 N/A 0.453±0.16 N/A 0.518±0.39
ENSMUST00000110065 0.772±0.17 0.486±0.20 0.486±0.00 0.594±0.38 3.851±0.87 1.009±0.48 0.353±0.01 0.289±0.21 0.059±0.03 1.309±0.29 0.052±0.02 1.218±0.55 0.099±0.05 0.416±0.18
ENSMUST00000110066 0.260±0.03 0.555±0.00 0.288±0.01 0.165±0.07 0.942±0.00 N/A N/A N/A 0.015±0.00 0.356±0.00 0.127±0.06 0.460±0.22 0.037±0.00 0.292±0.00
ENSMUST00000135684 N/A N/A N/A N/A N/A N/A N/A N/A 0.339±0.08 N/A N/A N/A 0.174±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005CC CIL_0005CC_0002 CGP 12:100549778-100896981
CIL_00038W CIL_00038W_0002 CGP 12:100779057-100908198
CIL_0001UN CIL_0001UN_0002 CGP 12:100876682-101028983

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0005886 IEA plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0032024 IMP positive regulation of insulin secretion
GO:0035774 IMP positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0045656 IMP negative regulation of monocyte differentiation
GO:0071467 IMP cellular response to pH
GO:2001206 IMP positive regulation of osteoclast development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053711 GPR68 G protein-coupled receptor 68 protein_coding Danio_rerio
ENSG00000119714 GPR68 G protein-coupled receptor 68 protein_coding Homo_sapiens

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