C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamic-oxaloacetic transaminase 1, soluble
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120053 GOT1 9606 - 10:99396870-99430624 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370508 GOT1-001 99396870-99430593 protein_coding
  ENST00000471741 GOT1-003 99420267-99430624 processed_transcript
  ENST00000489349 GOT1-002 99397465-99403749 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370508ENST00000489349
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370508 4.542±0.00 6.380±0.00 10.272±0.00 68.551±31.23 4.793±2.67 8.294±0.15 102.755±76.34 62.767±35.50 42.794±42.16 4.526±3.33 47.734±11.55 13.456±1.86 12.185±1.18 20.736±1.46
ENST00000489349 N/A N/A N/A N/A N/A N/A N/A 38.712±0.00 37.360±0.00 2.194±1.19 N/A N/A N/A 12.544±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00054U CIL_00054U_0001 CGP 10:99329099-99430624
CIL_00054T CIL_00054T_0001 CGP 10:99396870-99536524

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000096 TAS sulfur amino acid metabolic process
GO:0004069 ISS L-aspartate:2-oxoglutarate aminotransferase activity
GO:0004609 IEA phosphatidylserine decarboxylase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005764 IEA lysosome
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006094 TAS gluconeogenesis
GO:0006103 ISS 2-oxoglutarate metabolic process
GO:0006107 IEA oxaloacetate metabolic process
GO:0006114 ISS glycerol biosynthetic process
GO:0006531 ISS aspartate metabolic process
GO:0006532 IEA aspartate biosynthetic process
GO:0006533 IDA aspartate catabolic process
GO:0006536 ISS glutamate metabolic process
GO:0006595 TAS polyamine metabolic process
GO:0008483 TAS transaminase activity
GO:0008652 TAS cellular amino acid biosynthetic process
GO:0009058 IEA biosynthetic process
GO:0019509 TAS L-methionine biosynthetic process from methylthioadenosine
GO:0019550 IEA glutamate catabolic process to aspartate
GO:0019551 IEA glutamate catabolic process to 2-oxoglutarate
GO:0030170 IEA pyridoxal phosphate binding
GO:0031406 IEA carboxylic acid binding
GO:0032869 IEP cellular response to insulin stimulus
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0043648 IEA dicarboxylic acid metabolic process
GO:0043679 IEA axon terminus
GO:0044281 TAS small molecule metabolic process
GO:0047801 ISS L-cysteine:2-oxoglutarate aminotransferase activity
GO:0051384 IEP response to glucocorticoid
GO:0055089 IEA fatty acid homeostasis
GO:0070062 IDA extracellular vesicular exosome
GO:0080130 IEA L-phenylalanine:2-oxoglutarate aminotransferase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039093 got1 glutamic-oxaloacetic transaminase 1, soluble protein_coding Danio_rerio
ENSMUSG00000025190 Got1 glutamic-oxaloacetic transaminase 1, soluble protein_coding Mus_musculus

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