C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IQ motif and Sec7 domain 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120645 IQSEC3 9606 + 12:66765-178460 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000382841 IQSEC3-001 77376-171330 protein_coding
  ENST00000537151 IQSEC3-006 169055-175359 processed_transcript
  ENST00000538872 IQSEC3-002 66765-178460 protein_coding
  ENST00000540907 IQSEC3-003 168978-171466 retained_intron
  ENST00000544511 IQSEC3-005 176482-178454 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverLungMuscleOvaryTestisENST00000382841ENST00000537151ENST00000538872
Transcript ID Brain Breast Colon Heart Liver Lung Muscle Ovary Testis
ENST00000382841 N/A 0.040±0.00 0.059±0.00 N/A 0.055±0.00 0.398±0.00 N/A 0.088±0.00 N/A
ENST00000537151 N/A N/A 1.454±0.00 N/A 0.354±0.00 0.505±0.00 1.039±0.00 N/A N/A
ENST00000538872 5.699±4.26 0.729±0.00 0.377±0.00 0.129±0.11 0.041±0.01 N/A N/A N/A 0.478±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005086 IBA:IEA ARF guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0030036 IBA actin cytoskeleton organization
GO:0030054 IBA cell junction
GO:0032012 IEA regulation of ARF protein signal transduction
GO:0043547 IEA positive regulation of GTPase activity
GO:0045211 IEA postsynaptic membrane
GO:0060077 IEA inhibitory synapse

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075792 iqsec3a IQ motif and Sec7 domain 3a protein_coding Danio_rerio
ENSDARG00000093091 iqsec3b IQ motif and Sec7 domain 3b protein_coding Danio_rerio
ENSMUSG00000040797 Iqsec3 IQ motif and Sec7 domain 3 protein_coding Mus_musculus

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