C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IQ motif and Sec7 domain 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040797 Iqsec3 10090 - 6:121372933-121473678 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000046373 Iqsec3-001 121372933-121473678 protein_coding
  ENSMUST00000129815 Iqsec3-003 121372933-121473623 nonsense_mediated_decay
  ENSMUST00000151397 Iqsec3-004 121404801-121473678 retained_intron
  ENSMUST00000152103 Iqsec3-002 121372933-121473665 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046373ENSMUST00000129815ENSMUST00000151397ENSMUST00000152103
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046373 0.145±0.00 0.830±0.23 N/A 7.520±4.32 0.051±0.00 0.183±0.08 N/A N/A 0.026±0.00 N/A N/A N/A 0.020±0.01 0.068±0.03
ENSMUST00000129815 0.191±0.00 0.361±0.07 N/A N/A 0.141±0.00 0.076±0.00 N/A 0.023±0.00 N/A 0.017±0.01 0.113±0.06 0.058±0.02 0.012±0.01 0.050±0.02
ENSMUST00000151397 N/A N/A N/A N/A N/A N/A 0.127±0.02 N/A N/A 0.006±0.00 0.031±0.00 N/A N/A N/A
ENSMUST00000152103 0.196±0.06 1.039±0.42 0.025±0.01 7.442±7.12 0.252±0.09 0.210±0.08 0.128±0.03 0.036±0.02 0.013±0.01 0.021±0.02 0.105±0.06 0.063±0.03 0.007±0.00 0.050±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005086 IBA ARF guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005634 IBA nucleus
GO:0005737 IEA cytoplasm
GO:0030036 IBA actin cytoskeleton organization
GO:0030054 IBA cell junction
GO:0032012 IEA regulation of ARF protein signal transduction
GO:0043547 IEA positive regulation of GTPase activity
GO:0045211 IDA postsynaptic membrane
GO:0060077 IDA inhibitory synapse

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075792 iqsec3a IQ motif and Sec7 domain 3a protein_coding Danio_rerio
ENSDARG00000093091 iqsec3b IQ motif and Sec7 domain 3b protein_coding Danio_rerio
ENSG00000120645 IQSEC3 IQ motif and Sec7 domain 3 protein_coding Homo_sapiens

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