C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transforming growth factor, beta-induced, 68kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120708 TGFBI 9606 + 5:136028895-136063818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000442011 TGFBI-001 136028895-136063817 protein_coding
  ENST00000503087 TGFBI-017 136059186-136063372 protein_coding
  ENST00000504185 TGFBI-010 136028988-136046440 processed_transcript
  ENST00000504411 TGFBI-018 136061190-136063803 retained_intron
  ENST00000506699 TGFBI-007 136028991-136063816 retained_intron
  ENST00000507018 TGFBI-003 136029139-136063665 nonsense_mediated_decay
  ENST00000508076 TGFBI-016 136058849-136063815 protein_coding
  ENST00000508767 TGFBI-012 136047324-136054818 protein_coding
  ENST00000509485 TGFBI-013 136053943-136059145 nonsense_mediated_decay
  ENST00000509749 TGFBI-011 136047353-136049807 retained_intron
  ENST00000513497 TGFBI-015 136058767-136061536 retained_intron
  ENST00000514242 TGFBI-014 136055499-136059214 retained_intron
  ENST00000514554 TGFBI-008 136049516-136063818 protein_coding
  ENST00000515433 TGFBI-009 136045745-136055189 retained_intron
  ENST00000604555 TGFBI-019 136047418-136055392 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000442011ENST00000504411ENST00000506699ENST00000507018ENST00000508076ENST00000514554ENST00000515433
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000442011 66.330±0.00 32.437±0.00 2.114±0.00 1.611±1.23 30.224±8.47 13.399±6.43 13.883±8.25 11.957±2.27 18.198±4.24 32.209±19.20 11.255±7.69 32.148±19.76 159.321±54.36 11.661±11.02
ENST00000504411 N/A N/A N/A 0.702±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000506699 N/A N/A N/A 0.108±0.00 N/A N/A N/A N/A N/A 1.870±0.00 N/A N/A N/A N/A
ENST00000507018 N/A N/A N/A N/A N/A N/A N/A 6.966±0.00 N/A N/A N/A N/A N/A 8.439±0.00
ENST00000508076 32.982±0.00 26.302±0.00 N/A 3.116±0.00 21.024±0.00 17.468±0.00 N/A 12.634±0.00 12.643±0.00 30.717±0.00 N/A 13.769±0.83 N/A 23.269±0.00
ENST00000514554 32.947±0.00 22.717±0.00 N/A 0.932±0.00 19.986±0.00 15.949±0.00 7.013±0.00 4.878±0.00 5.908±0.00 13.350±0.00 5.811±0.00 11.079±5.05 N/A 11.009±10.52
ENST00000515433 N/A N/A N/A N/A N/A 0.598±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005XY CIL_0005XY_0001 CGP 5:135922279-136063818
CIL_0005P2 CIL_0005P2_0001 CGP 5:136028895-136188747

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEP angiogenesis
GO:0002062 IEA chondrocyte differentiation
GO:0005178 TAS integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005518 IPI collagen binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005604 IEA basement membrane
GO:0005615 IDA extracellular space
GO:0005802 IDA trans-Golgi network
GO:0005886 TAS plasma membrane
GO:0007155 IEA cell adhesion
GO:0007162 TAS negative regulation of cell adhesion
GO:0007601 IEA visual perception
GO:0008283 TAS cell proliferation
GO:0030198 IEA extracellular matrix organization
GO:0031012 IDA extracellular matrix
GO:0050840 IEA extracellular matrix binding
GO:0050896 IEA response to stimulus
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071586 tgfbi transforming growth factor, beta-induced protein_coding Danio_rerio
ENSMUSG00000035493 Tgfbi transforming growth factor, beta induced protein_coding Mus_musculus

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